It is intended to make the fluorination by means of simple methodologies in organic synthesis, obtaining diazonium salts at different positions of the benzene ring for later fluorination of them. The physic-chemical properties of thymol and carvacrol are expected to be considerably different after inclusion of the fluorine atoms, which may present properties of interest to areas such as medicinal chemistry and agrochemicals. For physic-chemical studies of the compounds, it is intended to use 1H and 19F NMR. In addition, theoretical calculations of electronic structure, using Functional Density Theory ("DFT") and/or ab initio, with several basis sets available in commercial software packages such as GAUSSIAN-09, may be used for comparison and elucidation of experimental results.
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