| Grant number: | 19/00088-1 |
| Support type: | Scholarships in Brazil - Scientific Initiation |
| Effective date (Start): | February 01, 2019 |
| Effective date (End): | January 31, 2020 |
| Field of knowledge: | Biological Sciences - Biochemistry - Molecular Biology |
| Cooperation agreement: | Max Planck Society for the Advancement of Science |
| Principal researcher: | Nubia Barbosa Eloy |
| Grantee: | Giovanna Araujo Boaventura |
| Home Institution: | Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil |
| Associated research grant: | 17/10333-8 - APC as an entry point to study small molecule regulation of the cell cycle, AP.JP |
Abstract The anaphase promoting complex (APC) is a multiprotein complex - an E3 ubiquitin ligase - involved in the ubiquitin-dependent proteolysis of cell cycle regulatory proteins, and in which we include the destruction of mitotic cyclins during the transition from metaphase to anaphase. Identification of the complete gene set encoding the APC subunits in Arabidopsis suggests that the basic processes controlled by ubiquitin-mediated proteolysis in plants are similar to those of other organisms. However, results from several groups indicate that APC has other specific functions during plant development regulation. | |
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