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Effect of xylooligosaccharides (XOS) obtained from sugarcane bagasse in the bactericidal action of Lactobacillus acidophylus and Lactobacillus rhamnosus GG

Grant number: 18/14552-9
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2018
Effective date (End): July 31, 2019
Field of knowledge:Engineering - Chemical Engineering
Principal Investigator:Raquel de Lima Camargo Giordano
Grantee:João Vitor Menezes Marçal
Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
Associated research grant:16/10636-8 - From the cell factory to the Biodiesel-Bioethanol integrated biorefinery: a systems approach applied to complex problems in micro and macroscales, AP.BIOEN.TEM


Bacteriocins are proteins/peptides that have bactericidal or bacteriostatic action. Industrially, foods are submitted to sterilization techniques that involve high temperatures or the application of chemical preservatives, which can cause side effects like allergies, indigestion and headaches. In this way, bacteriocins are a promising alternative in food preservation. Probiotics are live microorganisms that confer benefits to the health of the host. Among the most known probiotics, we can mention the lactobacilli, which produce bacteriocins. The growth of probiotic microorganisms is stimulated by prebiotic compounds, such as xylooligosaccharides (XOS), which are small oligomers of xylose (2-7 units) that can be obtained from a mild hydrolysis of hemicellulose. In this way, this work aims to evaluate the bactericidal and bacteriostatic action of Lactobacillus rhamnosus GG and Lactobacillus acidophilus broth grown in the presence of different XOS compositions obtained from sugarcane bagasse. The bactericidal activity will be evaluated through the formation of halos of inhibition in the growth of pathogenic bacteria, and the results will be used as a criterion for the selection of protocol for XOS production from sugarcane bagasse.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MILESSI, THAIS S.; CORRADINI, FELIPE A. S.; MARCAL, JOAO V. M.; BALDEZ, THAIS O.; KOPP, WILLIAN; GIORDANO, ROBERTO C.; GIORDANO, RAQUEL L. C.. Xylooligosaccharides production chain in sugarcane biorefineries: From the selection of pretreatment conditions to the evaluation of nutritional properties. INDUSTRIAL CROPS AND PRODUCTS, v. 172, . (18/14552-9, 16/10636-8, 18/06696-0)

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