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3D printing of regenerated silk fibroin via multiphoton lithography for microfabrication of photonic devices

Grant number: 18/11039-9
Support Opportunities:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): July 27, 2018
Effective date (End): June 26, 2019
Field of knowledge:Interdisciplinary Subjects
Principal Investigator:Cleber Renato Mendonça
Grantee:Moliria Vieira dos Santos
Supervisor: Fiorenzo Gabriele Omenetto
Host Institution: Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
Research place: Tufts University, United States  
Associated to the scholarship:16/11591-8 - Femtosecond laser micro-structuring in biopolymers of celulose and fibroin: fabrication of photonic devices, BP.PD


Silk fibroin are abundant natural polymers, which in the last years has been studied as an attractive high-technology material platform, offering new opportunities for photonics, optoelectronics applications. In the meantime, multiphoton lithography (MPL) has been explored as an attractive processing tool for spatially controlled polymerization of materials, which can be used to fabrication, for instance, of high-resolution complex 3D structures for creating functionalized optical interfaces. In this work, we propose the 3D printing of luminescent structures of regenerated silk fibroin (RSF) through noncontact and maskless MPL technique for microfabrication of photonic devices using femtosecond laser pulses in conjunction with specific photoinitiator chemistry. In this context, it will be necessary to determine the conditions for microfabrication, aimed at producing optical waveguides. Both, straight and curved waveguides will be patterned. Rare earth complexes will be added to silk waveguides as a gain medium, to further demonstrate the flexibility of this approach. In this sense, the implementation and execution of this project should provide results that contribute to the development of both points of view, basic and applied nonlinear optical devices, exploring new possibilities in materials processing and offering a new route for creating biophotonic elements that are biocompatible and biodegradable. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MARQUEZ, AUGUSTO; SANTOS, MOLIRIA V.; GUIRADO, GONZALO; MORENO, ALEX; AZNAR-CERVANTES, SALVADOR D.; CENIS, JOSE LUIS; SANTAGNELI, SILVIA H.; DOMINGUEZ, CARLOS; OMENETTO, FIORENZO G.; MUNOZ-BERBEL, XAVIER. Nanoporous silk films with capillary action and size-exclusion capacity for sensitive glucose determination in whole blood. LAB ON A CHIP, v. 21, n. 3, p. 608-615, . (18/11039-9, 16/11591-8)

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