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Comparison between APEC genomes and genomes of commensal Escherichia coli

Grant number: 17/21904-6
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): April 01, 2018
Effective date (End): June 30, 2018
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Renato Pariz Maluta
Grantee:Mariana Silveira Derami
Host Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:16/17421-7 - Comparison between the microbiomes of the respiratory tract of healthy chickens and chickens diagnosed with colibacillosis, AP.JP


The respiratory tract is a reservoir for several microorganisms. The presence of disease in the lungs alters the conditions necessary for microbial growth in the respiratory tract. Therefore, diseases in the respiratory tract may alter the composition of the resident microbiota. The association between microbiota and diseases is known. In poultry, for example, infection with the chicken infectious bronchitis virus (IBV) facilitates the colonization and production of Escherichia coli (colibacillosis) disease. E coli strains associated with colibacillosis are known as APEC (Avian Pathogenic E. coli). Genomes of APEC strains will be sequenced and annotated.These genomes will be compared to non-pathogenic E. coli genomes present in Genbank. This work may be useful in the definition of genetic traits associated with APEC. (AU)

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
DERAMI, Mariana Silveira. Comparison between the respiratory tract microbiome of healthy chickens and chickens diagnosed with colibacillosis. 2019. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia Campinas, SP.

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