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Prevalence and factors associated with pre-diabetes, undiagnosed diabetes and diabetes in people over 50 years of age

Grant number: 17/22820-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2018
Effective date (End): April 30, 2019
Field of knowledge:Health Sciences - Collective Health - Epidemiology
Principal researcher:Tiago da Silva Alexandre
Grantee:Eilane Souza Marques dos Santos
Home Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


Individuals with undiagnosed and, therefore, untreated diabetes are at increased risk of disease-related comorbidities and mortality. Furthermore, with the worldwide increase in the prevalence of obesity, surveillance of pre-diabetes and undiagnosed diabetes, as well as knowledge of its associated factors are crucial to understanding the extent of the problem and for health policies to be implemented. Thus, the present study aims to examine the prevalence and factors associated with pre-diabetes, undiagnosed diabetes and diagnosed diabetes in Brazilians and English people over 50 years of age. This is a cross-sectional study with data from 9,169 participants of the English Longitudinal Study of Aging (ELSA) in 2012, and 9,412 participants in the Longitudinal Study of Health and Well-being of Brazilian Elderly People (ELSI-Brazil) in 2015. The Diabetes classification will be performed through self-report of diabetes and glycated hemoglobin values following the recommendation of the American Diabetes Association. Participants will be divided into four groups: non-diabetic, pre-diabetic, diagnosed diabetics, and undiagnosed diabetics. The prevalence of diabetes conditions will be calculated with a 95% confidence interval. Multinomial regression models adjusted for factors known to be associated with diagnosed diabetes will be adopted to analyze factors associated with pre-diabetes, undiagnosed diabetes and diagnosed diabetes, with reference to the non-diabetic category. The hypothesis of the present study is that pre-diabetes and undiagnosed diabetes have a high prevalence in the population over 50 years of age and that the associated factors are different between England and Brazil and, due to socioeconomic and behavioral conditions, the prevalence is higher in the latter. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DOS SANTOS, EILANE SOUZA MARQUES; MAXIMO, ROBERTA DE OLIVEIRA; DE ANDRADE, FABIOLA BOF; DE OLIVEIRA, CESAR; LIMA-COSTA, MARIA FERNANDA; ALEXANDRE, TIAGO DA SILVA. Differences in the prevalence of prediabetes, undiagnosed diabetes and diagnosed diabetes and associated factors in cohorts of Brazilian and English older adults. PUBLIC HEALTH NUTRITION, v. 24, n. 13, p. 4187-4194, . (17/22820-0)

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