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Patterns and determinants of growth and body composition in children and adolescents with intellectual disability

Grant number: 17/13071-4
Support Opportunities:Scholarships in Brazil - Post-Doctorate
Effective date (Start): January 01, 2018
Effective date (End): March 31, 2022
Field of knowledge:Health Sciences - Medicine - Maternal and Child Health
Principal Investigator:Gil Guerra Júnior
Grantee:Fábio Bertapelli
Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated scholarship(s):19/07103-6 - Patterns and Determinants of Growth and Body Composition in Children and Adolescents with Intellectual Disability, BE.EP.PD


Growth disorders and obesity in youth are public health problem. Youth with intellectual disabilities (ID) have higher prevalence of obesity and growth disorders than the general population of youth without ID. In Brazil, there are no population-based research about the growth and body composition in youth with ID. The primary objective of this study is to examine the patterns and determinants of growth and overweight in youth with ID in the State of São Paulo. The secondary objective is to examine the body composition and its potential determinants in youth with and without ID. The accuracy of anthropometric data in detecting overweight in youth with and without ID will also be examined. This research will be developed through two phases. In the phase I, we will collect data on weight, height, and body circumferences to assess growth patterns and prevalence of overweight in youth with ID (5-18 years old, n = 1000); we will also construct growth charts for youth with ID. In the phase II, we will examine the body composition (percentage of fat, regional and total fat and lean mass, and bone mineral density and content) and its potential determinants (physical activity levels, sedentary behavior, sports participation, motor performance, sexual maturation, quality of sleep, eating patterns, comorbidities and sociodemographic factors) in youth with and without ID (5-18 years old, ID n = 50, without ID n = 50); the body fat using DXA will serve as a criterion for assessing the performance of body circumferences (neck and waist), and height/waist ratio in identifying overweight. This study is crucial to support clinical practice and epidemiological research to guide public policy in preventing growth disorders and reducing obesity in youth with ID. (AU)

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Scientific publications (6)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BERTAPELLI, FABIO; AGIOVLASITIS, STAMATIS; MOTL, ROBERT W.; SOARES, ROBERTO A.; DE BARROS-FILHO, MARCOS M.; AMARAL-JUNIOR, WILSON D.; GUERRA-JUNIOR, GIL. Development and Cross-Validation of a Prediction Equation for Estimating Percentage Body Fat From Body Mass Index in Young People With Intellectual Disability. ADAPTED PHYSICAL ACTIVITY QUARTERLY, v. 37, n. 4, p. 481-497, . (18/02677-1, 17/13071-4, 19/07103-6, 18/02795-4)
BERTAPELLI, F.; ALLRED, A. T.; CHOI, P.; PITCHFORD, E. A.; GUERRA-JUNIOR, G.; AGIOVLASITIS, S.. Predicting the rate of oxygen uptake from step counts using ActiGraph waist-worn accelerometers in adults with Down syndrome. JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, v. 64, n. 8, . (17/13071-4)
BERTAPELLI, FABIO; JOHNSON, MARQUELL; PITETTI, KEN; SMITH, MALLORY C.; CARLSON, BENJAMIN; CURTIS, JASMINE S.; AGIOVLASITIS, STAMATIS. Association between sleep quality and physical functioning in adults with Down syndrome: A brief report. DISABILITY AND HEALTH JOURNAL, v. 15, n. 1, . (17/13071-4, 19/07103-6)
FABIO BERTAPELLI; STAMATIS AGIOVLASITIS; ROBERT W. MOTL; MARCOS M. DE BARROS-FILHO; GIL GUERRA-JUNIOR. Estimation of body fat in children with intellectual disability: development and cross-validation of a simple anthropometric method. Jornal de Pediatria, v. 98, n. 5, p. 519-525, . (17/13071-4, 18/02677-1, 19/07103-6)
BERTAPELLI, FABIO; PITETTI, KEN; MILLER, RUTH A.; JAEGER, ADAM; LOOVIS, MICHAEL; DO AMARAL-JUNIOR, WILSON D.; DE BARROS-FILHO, MARCOS M.; GUERRA-JUNIOR, GIL. Comparing Motor Competence of Sex- and Age-Matched Youth With Intellectual Disability From Brazil and the United States. ADAPTED PHYSICAL ACTIVITY QUARTERLY, v. 37, n. 4, p. 423-440, . (18/02677-1, 17/13071-4, 19/07103-6, 18/02795-4)
STRAFACCI, AMANDA DE SOUSA LIMA; CAMARGO, JULIANA FERNANDES; BERTAPELLI, FABIO; GUERRA JUNIOR, GIL. Growth assessment in children with Williams-Beuren syndrome: a systematic review. JOURNAL OF APPLIED GENETICS, v. 61, n. 2, . (17/13071-4)

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