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Aplication of low-density dispersive liquid-liquid microextraction (LDS-DLLME) to identify new psychoactive substances in plasma by LC-MS/MS

Grant number: 17/12850-0
Support type:Scholarships in Brazil - Master
Effective date (Start): November 01, 2017
Effective date (End): March 31, 2019
Field of knowledge:Biological Sciences - Pharmacology - Toxicology
Principal researcher:José Luiz da Costa
Grantee:Thais Lino da Silva
Home Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

New psychoactive substances (NPS) are synthetic drugs of abuse that provide users similar effects to those produced by "traditional" drugs, but most are not controlled by international agencies and agencies. Currently, the use of NPS has become a major public health problem worldwide, with reports of serious poisoning and deaths due to abusive use of these increasingly recurrent drugs. The objective of this project was to optimize, validate and implement a qualitative analytical methodology by HPLC-MS/MS, one of the main techniques for drug and drug analysis, which offers high sensitivity and identification capacity for toxicological analyzes. (AU)

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SILVA, Thais Lino da. Avaliação tardia do estado de saude de pessoas intoxicadas agudamente por agrotoxicos inibidores das colinesterases. 2004. 73 f. Master's Dissertation - Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas Campinas, SP.

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