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Epidemiological study of Dengue (serotypes1-4), Zika e Chikungunya in a cohort of São José do Rio Preto, São Paulo, Brazil: analysis of the first wave results

Grant number: 17/09671-6
Support Opportunities:Scholarships abroad - Research
Effective date (Start): August 14, 2017
Effective date (End): February 13, 2018
Field of knowledge:Health Sciences - Collective Health - Epidemiology
Principal Investigator:Francisco Chiaravalloti Neto
Grantee:Francisco Chiaravalloti Neto
Host Investigator: Marta Blangiardo
Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: Imperial College London, England  
Associated research grant:13/21719-3 - Epidemiological study of dengue (serotypes1-4) in a cohort of São José do Rio Preto, São Paulo, Brazil, during 2014-2018, AP.TEM


The present proposal links with the thematic project titled "Epidemiological study of Dengue (serotypes1-4), Zika and Chikungunya in a cohort of São José do Rio Preto, São Paulo, Brazil" (FAPESP Process # 2013/21719-3). The main goal of this proposal is to study the obtained data of the first wave of the thematic project that was developed in 2016 (results of laboratorial tests, of questionnaires and mosquito adult collections). The specific objectives are to measure and map the prevalence of dengue, zika and chikungunya occurrence in the study area; to evaluate the relationship between these prevalence and individual and context covariates; to measure and map in space and time the vector infestation; and to evaluate the relationship between the vector infestation and the dengue, zika and chikungunya prevalence. Since these phenomena were measured in space (dengue, zika and chikungunya) and space and time (vector infestation), it will be necessary to allow for correlation in space and time. In this sense, the hierarchical approach is the most appropriate way to take into account the spatial and temporal dependency of the study phenomena. Furthermore, if the zero proportions are substantial, it will be necessary to consider zero-inflated distributions. Spatial, temporal and spatio-temporal dependency and zero-inflated distribution will be considered in a Bayesian context and with the use of a recently developed approach named as INLA (Integrated Nested Laplace Approximations) that provides computationally fast and accurate results.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MORALEJO BERMUDI, PATRICIA MARQUES; CARNEIRO CASTRO COSTA, DANIELLE NUNES; NUNES, CANIS MARONI; TOLEZANO, JOSE EDUARDO; HIRAMOTO, ROBERTO MITSUYOSHI; COLEBRUSCO RODAS, LILIAN APARECIDA; CIPRIANO, RAFAEL SILVA; BLANGIARDO, MARTA; CHIARAVALLOTI-NETO, FRANCISCO. Canine serological survey and dog culling ant its relationship with human visceral leishmaniasis in an endemic urban area. BMC INFECTIOUS DISEASES, v. 20, n. 1, . (14/17764-6, 14/06518-4, 16/25878-7, 17/09671-6)
CHIARAVALLOTI-NETO, FRANCISCO; DA SILVA, RAFAEL ALVES; ZINI, NATHALIA; DUTRA DA SILVA, GISLAINE CELESTINO; DA SILVA, NATAL SANTOS; PEREIRA PARRA, MAISA CARLA; DIBO, MARGARETH REGINA; ESTOFOLETE, CASSIA FERNANDA; FAVARO, ELIANE APARECIDA; DUTRA, KARINA ROCHA; et al. Seroprevalence for dengue virus in a hyperendemic area and associated socioeconomic and demographic factors using a cross-sectional design and a geostatistical approach, state of SAo Paulo, Brazil. BMC INFECTIOUS DISEASES, v. 19, . (13/21719-3, 15/12295-0, 17/09671-6)

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