Advanced search
Start date

Carotenoids extraction from Bactris gasipaes with ionic liquids and its application in metabolic programming model

Grant number: 16/23242-8
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): June 01, 2017
Effective date (End): December 31, 2020
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Science
Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
Principal Investigator:Veridiana Vera de Rosso
Grantee:Leonardo Mendes de Souza Mesquita
Host Institution: Instituto de Saúde e Sociedade (ISS). Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Santos , SP, Brazil
Associated scholarship(s):18/10705-5 - Extraction of Bactris gasipaes carotenoids using aqueous solutions of tensoactive Ionic liquids and common surfactants: a green and sustainable chemistry approach, BE.EP.DR


The application of ionic liquids (LI) in extraction processes is a viable alternative that follows the principles of green chemistry, optimizing the obtaining of industrial interest molecules in sustainable processes with lower generation of toxic waste. The Ministry of Health regulates the use of organic solvents Convention for the extraction of bioactive compounds in food, allowing the residual organic solvent (varying according to chemical species) is only in the range of 1 to 10 mg / kg of processed food, very low values that make this extremely limited use. Functional foods are excellent choices for prevention of chronic noncommunicable diseases (NCDs). Obesity is a multifactorial disease that can result from a fetal programming, characterized by chronic inflammation resulting low degree of excess intake of saturated fatty acids and / or trans fatty acids. The intrauterine environment has crucial role in the development of diseases in adulthood. The concept of nutritional metabolic programming assumes that inadequate maternal nutrition during pregnancy and lactation can promote permanent changes during fetal development period and neonate. Thus the objective of the project is to develop and optimize an extraction method using ionic liquids, to obtain carotenoids from the pulp of the fruit of peach palm (Bactris gasipaes), which can be used as natural pigments and additives in the food industry, and testing the extracts on metabolic programming model. The project foresees the development of a new methodology for carotenoid extraction and its application to health promotion and the search for this food matrix, little explored and discarded. Moreover, the application of these extracts in metabolic programming models is unprecedented, and will generate new strategies for the treatment and prevention of obesity. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE SOUZA MESQUITA, LEONARDO M.; VENTURA, SONIA P. M.; BRAGA, ANNA R. C.; PISANI, LUCIANA P.; DIAS, V, ANA C. R.; DE ROSSO, VERIDIANA V.. Ionic liquid-high performance extractive approach to recover carotenoids from Bactris gasipaes fruits. GREEN CHEMISTRY, v. 21, n. 9, p. 2380-2391, . (16/23242-8, 16/18910-1)
DE SOUZA MESQUITA, LEONARDO M.; MURADOR, DANIELLA CARISA; NEVES, BRUNA VITORIA; CAVALCANTE BRAGA, ANNA RAFAELA; PISANI, LUCIANA PELLEGRINI; DE ROSSO, VERIDIANA VERA. Bioaccessibility and Cellular Uptake of Carotenoids Extracted from Bactris gasipaes Fruit: Differences between Conventional and Ionic Liquid-Mediated Extraction. Molecules, v. 26, n. 13, . (16/23242-8, 16/18910-1)
DE SOUZA MESQUITA, LEONARDO M.; MENNITTI, V, LAIS; DE ROSSO, VERIDIANA V.; PISANI, LUCIANA P.. The role of vitamin A and its pro-vitamin carotenoids in fetal and neonatal programming: gaps in knowledge and metabolic pathways. NUTRITION REVIEWS, v. 79, n. 1, p. 76-87, . (19/09359-8, 16/18910-1, 16/23242-8, 16/14133-0)
DE SOUZA MESQUITA, LEONARDO M.; MARTINS, MARGARIDA; MARICATO, ELIA; NUNES, CLAUDIA; QUINTEIRO, PAULA S. G. N.; DIAS, V, ANA C. R.; COUTINHO, JOAO A. P.; PISANI, LUCIANA P.; DE ROSSO, VERIDIANA V.; VENTURA, SONIA P. M.. Ionic Liquid-Mediated Recovery of Carotenoids from the Bactris gasipaes Fruit Waste and Their Application in Food-Packaging Chitosan Films. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 8, n. 10, p. 4085-4095, . (18/10705-5, 16/23242-8, 16/18910-1)
DE SOUZA MESQUITA, LEONARDO M.; NEVES, BRUNA VITRIA; PISANI, LUCIANA PELLEGRINI; DE ROSSO, VERIDIANA VERA. Mayonnaise as a model food for improving the bioaccessibility of carotenoids from Bactris gasipaes fruits. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 122, . (16/23242-8, 16/18910-1)
DE SOUZA MESQUITA, LEONARDO M.; MARTINS, MARGARIDA; PISANI, LUCIANA P.; VENTURA, SONIA P. M.; DE ROSSO, VERIDIANA V.. Insights on the use of alternative solvents and technologies to recover bio-based food pigments. COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, v. 20, n. 1, . (16/23242-8, 16/18910-1, 18/10705-5)
DE SOUZA MESQUITA, LEONARDO M.; CASAGRANDE, BRENO P.; SANTAMARINA, ALINE B.; SERTORIO, MARCELA N.; DE SOUZA, DANIEL VITOR; MENNITTI, LAIS V.; JUCA, ANDREA; JAMAR, GIOVANA; ESTADELLA, DEBORA; RIBEIRO, DANIEL ARAKI; et al. Carotenoids obtained from an ionic liquid-mediated process display anti-inflammatory response in the adipose tissue-liver axis. FOOD & FUNCTION, v. 12, n. 18, . (16/23242-8, 16/18910-1)

Please report errors in scientific publications list by writing to: