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Correlation between exercise tolerance evaluated by the cooper test and cardiovascular function with quality of life in patients with heart failure and reduced ejection fraction

Grant number: 16/09834-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): November 01, 2016
Effective date (End): October 31, 2017
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Meliza Goi Roscani
Grantee:Luiz Antônio Souza de Araújo
Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


There is great interest in determining easily reproducible, feasible, and cost-effective methods for clinical and prognostic assessment of patients with heart failure (HF).The 6-minute walk test has been of great importance to assess the exercise tolerance of these patients. Nevertheless, the 12-minute walk test or Cooper test has not been extensively studied in patients with HF. This study aims to evaluate the potential use of Cooper test in patients with heart failure and reduced left ventricular ejection fraction (LVEF).We understand that this test evaluates the patient over a longer period of time, therefore, allows more reliable data, reducing the effect of previous training and improving the quality of collected variables such as heart rate, blood pressure, and distance traveled. This study will also allow the comparison of results between active and sedentary individuals, adding to the many studies showing that physical exercise (PE) has shown beneficial effects on quality of life and functional capacity of patients with heart failure (HF) regardless of left ventricular ejection fraction value (LVEF).Objectives: To compare the recovery rate of cardiac frequency and distance covered in Cooper test for active and sedentary patients. And find the correlation of these values with the quality of life. Methodology: Cross-sectional prospective study in HF patients with less than 50% LVEF, which are classified in two groups, sedentary (S) and non-sedentary (NS), based IPAQ questionnaire. The patients will undergo physical and clinical assessment, the walk test, echocardiography and questionnaire of quality of life SF-36.Expected results: we expected to find correlation between the distance walked in the walk test, the rate of recovery of cardiac frequency and quality of life with the degree of physical inactivity, regardless of the degree of systolic left ventricular dysfunction, as assessed by ejection fraction echocardiogram. (AU)

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