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Mitochondrial function and residual feed intake in association with glycerin to Nellore cattle in feedlot

Grant number: 16/13260-9
Support type:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): October 10, 2016
Effective date (End): July 21, 2017
Field of knowledge:Agronomical Sciences - Animal Husbandry - Animal Nutrition and Feeding
Principal researcher:Jane Maria Bertocco Ezequiel
Grantee:Robson Sfaciotti Barducci
Supervisor abroad: Monty Kerley
Home Institution: Instituto de Zootecnia. Agência Paulista de Tecnologia dos Agronegócios (APTA). Secretaria de Agricultura e Abastecimento (São Paulo - Estado). Nova Odessa , SP, Brazil
Research place: University of Missouri, Columbia (UM), United States  
Associated to the scholarship:15/01522-6 - Mitochondrial function and residual feed intake in association with glycerin to Nellore cattle in feedlot., BP.PD

Abstract

As in recent years, the price of concentrated ingredients used in cattle feed has increased to the point of interfering with the at sign production cost, understanding the genetic,cellular and biochemical mechanisms responsible for feed efficiency (EA) or residual feedintake (RFI) are important for the production of meat, especially when byproducts are used inplace of corn. Although breeds and diets can affect mitochondrial function, no studies haveinvestigated altercations in mitochondrial function due to differences in CAR phenotype ofconfined Nellore supplemented with glycerin. Therefore, the possibility arises that the ME in Nellore cattle occurs through mitochondrial function. Because of this assumption, theobjective of this project is determine if a relationship between the concentration ofmitochondrial protein (complex I and III) of Nellore cattle in feedlot in different phenotypes RFI supplemented with crude glycerin. The design will be completely randomized and the animal as the experimental unit. It will be used seventy uncastrated male Nellore cattle, with an average initial weight of ± 335 kg, which will remain in feedlot and fed for 84 days. The 14 cattle with higher RFI and 14 with lower RFI will be classified as high and low RFI groups, and in each group seven cattle will be fed with 0% and seven cattle will be fed with 20% crude glycerin until slaughter. Blood samples will be collected one week before slaughter foranalysis. If this hypothesis have confirmed, will help to show that the glycerin, helps toprovide animals with better ME, and the development of tools (biomarkers) to assistcompanies in improving efficient selection of animals that, in turn, help to maintain viablelivestock in Brazil and around the world.

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