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Optimization of the solvent mixture for extraction of phenolic compounds with antioxidant and antiproliferative activities from Byrsonima basiloba Juss. leaves by applying the i-optimal design

Grant number: 15/24919-9
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2016
Effective date (End): April 30, 2017
Field of knowledge:Engineering - Chemical Engineering - Chemical Technology
Principal Investigator:Catarina dos Santos
Grantee:Thais Cândido Roberto
Host Institution: Faculdade de Ciências e Letras (FCL-ASSIS). Universidade Estadual Paulista (UNESP). Campus de Assis. Assis , SP, Brazil


Phenolic compounds and flavonoids have antioxidant activity which usually has been related to the prevention of diseases such as cancer, diabetes, arthritis and anti- inflammatory processes. Plants of Byrsonima species, which belong to B. basiloba, are recognized for their antibacterial, antifungal, antimutagenic activities, among others. In order to obtain a higher content of phenols and/or flavonoids and with the greatest possible antioxidant activity, it will be done an i- optimal design for choosing the best ratio of solvent (water, methanol and ethanol) from the leaves of B . basiloba.

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