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Comparative angiographic study of diabetic and non-diabetic patients with critical limb ischemia

Grant number: 15/15754-6
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2016
Effective date (End): April 30, 2017
Field of knowledge:Health Sciences - Medicine - Surgery
Principal Investigator:Winston Bonetti Yoshida
Grantee:Giovanni Ortale Trainotti
Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

Context The PAD affects mainly patients with risk factors for atherosclerosis. Diabetics have about 5-15 times more likely to develop atherosclerotic arterial disease in relation to non diabetics and these alterations are more prevalent in distal arteries. Few studies have marked the distribution and severity of the arterial changes in diabetics compared with non-diabetics and its correlation with risk factors. Objectives: Compare the peripheral arterial changes shown in angiographic study of diabetic and non-diabetic patients with critical limb ischemia and compare these with the risk factors. Methods: There will be Retrospective study of patients with angiography of lower limbs and critical limb ischemia, peripheral arterial comparing changes between diabetics and non-diabetics, from 2009 to 2014. The sample size was calculated in 140 patients. Will be included good quality angiograms and excluded arteriography of the upper limbs, other diseases, lack of information in the medical record, previous vascular restorations. The changes will be evaluated using angiographic scores (TASC II and Bollinger). In addition, demographic and atherosclerotic risk profile will be pooled for both groups and compared using chi-square test, Fisher's exact test, and logistic regression.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GIOVANNI ORTALE TRAINOTTI; JAMIL VICTOR MARIÚBA; MATHEUS BERTANHA; MARCONE LIMA SOBREIRA; RICARDO DE ALVARENGA YOSHIDA; RODRIGO GIBIN JALDIN; PAULA ANGELELI BUENO DE CAMARGO; WINSTON BONETTI YOSHIDA. Comparação das alterações angiográficas entre pacientes diabéticos e não diabéticos com doença arterial periférica. Jornal Vascular Brasileiro, v. 22, . (15/15754-6)

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