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Qualitative comparison among four different ventilatory modalities applied in prolonged anesthetic procedures in rabbits positioned in lateral recumbency

Grant number: 15/26543-6
Support type:Scholarships in Brazil - Master
Effective date (Start): May 01, 2016
Effective date (End): July 31, 2017
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal researcher:Newton Nunes
Grantee:Eveline Simões Azenha Aidar
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


Currently, the use of different ventilation modalities is increasing in Veterinary Anesthesiology. But most of the research in this area uses the human medicine as a reference, as publications and experiments are not advanced in veterinary medicine. Maintaining a proper respiratory function is essential for a safe and effective anesthesia. It is known that patient recumbency and the use of analgesics such as opioids alter the respiratory dynamics, interfering with hemodynamic balance and anesthetic stability. Long procedures associated with the use of opioids are common in veterinary medicine such as orthopedic procedures. In this study, spontaneous ventilation, pressure control ventilation, pressure control ventilation with positive end-expiratory pressure and synchronized intermittent mandatory ventilation will be qualitatively compared. The ventilation modalities will be compared in four different groups of rabbits anesthetized with isoflurane during two hours and placed in the lateral recumbency. Cardiovascular and respiratory variables will be recorded at different moments and after, the results will be statistically evaluated by the least squares method, followed by the Tukey - Kramer test (p <0.05). (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
E.S.A. AIDAR; A.P. GERING; C. K. IDO; F.D.L. ROCHA; H.R.A. SILVA; P.E.S. SILVA; M. HORR; J.C. SILVA FILHO; N. NUNES. Parâmetros hemodinâmicos e ventilatórios em coelhos anestesiados com isoflurano, submetidos à ventilação controlada à pressão com ou sem PEEP. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 72, n. 3, p. 843-852, . (15/26543-6, 13/25655-0)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
AIDAR, Eveline Simões Azenha. Different ventilatory modalities during prolonged anesthesia in rabbits positioned in lateral recumbency. 2017. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.

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