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Glucose postprandial response and digestibility of diets with high and low resistant starch contend to old and adult dogs

Grant number: 15/26807-3
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): March 01, 2016
Effective date (End): February 28, 2017
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal researcher:Aulus Cavalieri Carciofi
Grantee:Mariana Gilbert Pescuma
Home Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


Resistant starch (RS) is characterized by the sum of non-digested and non-absorbed starch and starch degradation products, been fermented on large intestine. As not degraded by a-amylase, it is a starch fraction with physiologic effects similar with the fiber. Their benefits to human health was studied, however little is known for dogs. Starch is the main nutrient responsible to glucose postprandial fluctuations, therefore it is expected that the consumption of foods with higher RS content induce lower glucose postprandial increase. This could be important to old dogs, as studies had shown reduced insulin sensitivity for this age group. This way, the objective of this study is to evaluate on old and adult dogs the glucose postprandial response and nutrient digestibility of the same formulation, extruded to achieve high and low RS content. Sixteen beagle dogs will be used, 8 old dogs (more the 10 years old) and 8 adult dogs (between 2 to 6 years old). Experiment will follow a 2 x 2 factorial arrangement, with 2 diets (high and low RS) and 2 ages (old and adult), totaling 4 treatments. It will be organized in a cross over design: each age group will be divided in 2 subgroup of 4 dogs (portion of the cross over), that will be fed randomly on experimental diet during a period of 35 days. On the following period, the diets will be changed and all dogs will be fed the two diets (8 repetitions per treatment). Each period will include: day 1 to 28 for diet adaptation; day 29 to 34 for feces collection for digestibility analysis; day 35 for glucose postprandial evaluation. Data will be submitted to analysis of variance, considering the diet, age, and period effects, as well its interactions. Repeated measures analysis of variance with two factors inside the dogs (diet and sampling time), and one factor between dogs (diet) will be used to evaluate the effects of diet and time on the glucose postprandial changes. Mean comparisons will be done with the Tukey test. Values of P<0.05 will be consider significant and P<0.10 as trends.

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