Animals selected for rapid growth and increased muscle deposition also have higher carcass fat deposition. Excess of fat deposited in the carcass is a negative factor for production considering the processing cost and the depreciation in the value of the product. The fat deposition is a trait controlled by several genes involved in lipid metabolism. The identification of genetic components responsible for a part of the observed variation is fundamental for breeding programs thus allowing the selection of animals showing traits of economic interest. The objective of this study is to identify genomic regions, putative candidate genes and possible causative mutations controlling abdominal fat deposition in Brazilian chicken populations. For this purpose, the imputation of SNPs identified in parental lines from F2-TC and TT populations in genotyped chickens will be performed as well, GWAS analysis using haplotype information. The parental lines re-sequencing was performed previously (28 parental chickens from F2-TC population and 14 parental chickens from TT population) and these animals will be used as reference population to perform genotype imputation. Those analyses can improve the power to detect QTL as well as the chances to identify functional mutations. In addition, this proposed study will help us to understand the process of fat deposition in chickens and the molecular mechanisms involved.
News published in Agência FAPESP Newsletter about the scholarship: