Scholarship 14/02843-8 - Insetos hematófagos, Carrapatos - BV FAPESP
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Hematophagy in female Rhipicephalus sanguineus L. S. (Acari: Ixodidae) and its relations: biochemical (bioactive gifts in extracts) and morphophysiological (salivary gland and gut)

Grant number: 14/02843-8
Support Opportunities:Scholarships in Brazil - Doctorate (Direct)
Start date until: May 01, 2015
End date until: July 31, 2018
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Pathology
Principal Investigator:Maria Izabel Souza Camargo
Grantee:Elen Fernanda Nodari
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil

Abstract

Ticks are arthropod ectoparasites of great medical and veterinary importance, since it causes lesions in hosts, and transmit to pathogens. In this group, Rhipicephalus sanguineus (Latreille, 1806 ) stands out for its wide distribution on all continents and parasitize mainly the domestic dog. The ticks are required by hematophagous organisms have bodies that allow this process have great success in achieving both food, the digestion of blood components through respectively the salivary gland and intestine. The enzyme used arsenal comprises elements such as acid phosphatase, the calreticulinas and cathepsins, so the study of these different organs becomes very important to know the mode of action of these proteins that can generate new subsidies for the acquisition and development of new methods of control of these ectoparasites such as vaccines. Thus, this project will be aimed at identifying the presence of proteolytic enzymes, calreticulim and esterases (acid phosphatases) present in the salivary glands and gut of Rhipicephalus sanguineus female ticks fed on hosts (rabbits) immunized and not immunized. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
RODRIGUES, LEANDRO; GIGLIOTI, RODRIGO; GOMES, ANA CAROLINA PERONI; KATIKI, LUCIANA MORITA; OTSUK, IVANI POZAR; DA SILVA MATOS, RENATA; NODARI, ELEN FERNANDA; VERISSIMO, CECILIA JOSE. In Vitro Effect of Volatile Substances from Eucalyptus Oils on Rhipicephalus microplus. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 30, n. 5, p. 737-742, . (14/02843-8, 14/13143-7)
DE ABREU, MARINA RODRIGUES; PEREIRA, MELISSA CAROLINA; SIMIONI, PATRICIA UCELLI; NODARI, ELEN FERNANDA; PAIATTO, LISIERY NEGRINI; CAMARGO-MATHIAS, MARIA IZABEL. Immunomodulatory and morphophysiological effects of Rhipicephalus sanguineus s. l. (Acari: Ixodidae) salivary gland extracts. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, v. 207, p. 36-45, . (18/02999-9, 14/02843-8, 15/20745-6, 13/20258-2)
PEREIRA, MELISSA CAROLINA; NODARI, ELEN FERNANDA; DE ABREU, MARINA RODRIGUES; PAIATTO, LISIERY NEGRINI; SIMIONI, PATRICIA UCELLI; CAMARGO-MATHIAS, MARIA IZABEL. Rhipicephalus sanguineus salivary gland extract as a source of immunomodulatory molecules. Experimental and Applied Acarology, v. 83, n. 3, . (19/02831-3, 18/02999-9, 15/20745-6, 14/02843-8)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)

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