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Effect of seed chia (Salvia hipânica L.) in metabolism glucose and lipid of mice models of insulin resistance induced obesity

Grant number: 14/22574-1
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): April 01, 2015
Effective date (End): September 30, 2016
Field of knowledge:Biological Sciences - Physiology - Physiology of Organs and Systems
Principal Investigator:Luciana Chagas Caperuto
Grantee:Pâmella Hubinger Queiroz dos Santos
Host Institution: Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF). Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Diadema , SP, Brazil

Abstract

The obesity-associated insulin resistance affects largely the world population, due to a hypercaloric diet and hyperlipidemic linked to a sedentary lifestyle. Increasingly people trying to take their routine functional foods ensure the maintenance of health and inhibit the development of diseases such as hypertension, cancer, diabetes, obesity, and resistance insulin. It is in this scenario that the Chia seed (Salvia hispanica L.), the highest plant source of omega-3, proved a great candidate functional food that eases symptoms related to obesity and insulin resistance. Thus, the goal of this project is to evaluate the potential effect of ingesting Salvia hispanica L. seed as anti-inflammatory and endurance insulin in obese mouse model induced calorie diet.

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