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Comparison of electrocardiogram in patients with heart failure reduced ejection fraction and non sedentary and sedentary behavior

Grant number: 14/12339-5
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): January 01, 2015
Effective date (End): December 31, 2015
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Meliza Goi Roscani
Grantee:Letícia Vecchi Leis
Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


Purpose: Heart failure (HF) is a multifactorial syndrome, considered the leading cause of hospitalizations for cardiovascular diseases and significant factor related to worsening of quality of life. There is consensus that non sedentary behavior improves cardiac function and quality of life in patients with HF with reduced ejection fraction (LVEF), The current studies demonstrate that electrocardiogram (EKG), although non diagnosis, is important in screening of heart failure and some of its changes such as increased PR interval and QRS duration are effective markers of poor prognosis in patients with HF. Moreover, the EKG is technically easy access, low cost and rapid execution. Considering that in patients with HF and reduced LVEF, EKG changes are correlated with a worse cardiovascular prognosis and, also, there is relationship between sedentary behavior and worse cardiovascular capacity, we suspect that electrocardiographic changes suggestive of poor prognosis are found in patients with HF and reduced LVEF with sedentary behavior. Objectives: To compare the electrocardiographic abnormalities presented in patients with non sedentary and sedentary behavior in patients with HF and reduced LVEF and associate them to cardiovascular function and quality of life scale. Methodology: A cross sectional prospective study in 40 patients with HF with reduced LVEF. Evaluation of sedentary behavior and quality of life will be performed. After, two groups will be composed: Sedentary (S) and non-sedentary (NS). Clinical assessment, physical examination, electrocardiogram and echocardiogram will be performed for statistical comparison between the two groups. Expected Results: We expect to find electrocardiographic abnormalities in the S group that correlates with worsening cardiovascular function and quality of life. (AU)

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