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Evaluation of quality of life and functional capacity in obese with Chronic Obstructive Pulmonary Disease (COPD) associated with Obstructive Sleep Apnea Syndrome (OSA)

Grant number: 14/18965-5
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): January 01, 2015
Effective date (End): December 31, 2015
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal Investigator:Francis Lopes Pacagnelli
Grantee:Maiara Almeida Aldá
Host Institution: Pró-Reitoria de Pesquisa e Pós-Graduação. Universidade do Oeste Paulista (UNOESTE). Presidente Prudente , SP, Brazil


Beyond the epidemiological relations of the association between COPD and OSA, as well as the cardiovascular and metabolic consequences, it's primordial to emphasize the obesity's influence, becoming evident that the interaction between COPD, OSA, and obesity can, somehow, raise the cardiovascular risk and the probability of death, and also concur to worse the quality of life and the functional capacity. Objective: this present review aims to verify the life quality and the functional capacity in obese patients linked to COPD and OSA. Methods: will be selected 116 obese individuals with moderate, severe, and very severe COPD. The diagnosis of COPD by spirometry will be performed and patients must present a body mass index (BMI)> 27 kg/m2. Later, they will undergo polysomnography to confirm the diagnosis of OSA. With this, will be formed two groups: (1) COPD associated with obesity without OSA (58 patients) and (2) COPD associated with obesity with OSA (58 individuals). Specific questionnaires will be assessing the degree of dyspnea ["Modified Medical Research Council (MMRC)" modified], quality of life [Questionnaire Saint George's Respiratory (SGRQ)] and sleep scales ("Berlin Questionnaire" and "scale Epworth daytime sleep "). In addition, testing will be performed six-minute gait. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ALDA, MAIARA ALMEIDA; MUNGO PISSULIN, FLAVIO DANILO; THERESA WEBER, SILKE ANNA; BENETI, RICARDO; LEITE, MARCELI ROCHA; PACAGNELLI, FRANCIS LOPES. Clinical impact of chronic obstructive pulmonary disease (COPD) verified by the COPD Assessment Test (CAT) can be associated with functional capacity?. ACTA SCIENTIARUM-HEALTH SCIENCES, v. 40, . (14/18965-5)
MUNGO PISSULIN, FLAVIO DANILO; PACAGNELLI, FRANCIS LOPES; ALDA, MAIARA ALMEIDA; BENETI, RICARDO; DE BARROS, JEFFERSON LUIS; MINAMOTO, SUZANA TANNI; THEREZA WEBER, SILKE ANNA. Tríade síndrome da apneia obstrutiva do sono, DPOC e obesidade: sensibilidade de escalas de sono e de questionários respiratórios. Jornal Brasileiro de Pneumologia, v. 44, n. 3, p. 202-206, . (14/18965-5)

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