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Study about the reduction of oxidative stress in equine semen from the addition of quercetin on freezing and cooling extenders

Grant number: 14/01681-4
Support type:Scholarships in Brazil - Master
Effective date (Start): September 01, 2014
Effective date (End): February 29, 2016
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Reproduction
Cooperation agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
Principal researcher:Frederico Ozanam Papa
Grantee:Luis Fernando Mercês Chaves Silva
Home Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


The emergence of biotechnologies applied to equine semen, such as cooling and freezing procedures, represented a breakthrough for equine business, especially for allowing a better use of the ejaculate, thus optimizing the use of genetically superior animals. However, during these processes, seminal plasma is removed and also numerous antioxidant substances are eliminated, making sperm cells more susceptible to damages caused by the action of Reactive Oxygen Species (ROS). The incorporation of elements that perform this antioxidant function to cooling and freezing semen extenders is than necessary. Quercertin is considered a powerful antioxidant as it reduces the formation of the main ROS but its application on equine semen during the cryopreservation process is poorly referenced. Further studies are needed in order to determine if there is in fact a positive influence of its use in equine semen cooling and freezing protocols. (AU)

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SILVA, Luis Fernando Mercês Chaves. Study about the reduction of oxidative stress in equine semen from the addition of quercetin on cooling and freezing extenders. 2016. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Medicina Veterinária e Zootecnia. Botucatu Botucatu.

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