Evaluation and analytical application of boron doped diamond porous electrodes for voltammetric determination of biomolecules, ascorbic acid, uric acid, dopamine and adrenaline in biological fluids and/or pharmaceutical formulations

Abstract

In recent years new carbon materials have been used as working electrode and have drawn attention due to the excellent results obtained.The films of porous boron doped diamond (BDD) are a new class of hybrid materials carbon and have potential relevance for applications in electroanalysis due to their interesting electrochemical properties. This hybrid material combines excellent conductivity and electron transport of the electrodes of carbon nanotubes (CNTs) with rugged surface of BDD films with high content of carbon sp3.The use of electroanalytical techniques for the determination of organic and inorganic compounds has grown significantly since it takes, accurate sensitive, low cost and require short analysis times and in many cases the simple preparation of samples.Thus, the aim of this study is to evaluate the analytical potential of a porous BDD electrode performing fundamental studies related to the electrochemical behavior of this, comparing it with conventional electrodes (BDD flat) and vertically aligned carbon nanotubes (VACNTs). Additionally, after evaluate of the use of the electrode for the determination of some important biomolecules whose electrochemical behavior is known, its can still be applied in the determination of compounds of interest (analytes) in environmental, pharmaceutical or food with the evaluation of analytical conditions for the development of a good procedure.Moreover, if necessary, these porous BDD electrodes can be modified with surface treatments as well as planar BDD to improve their analytical performance (analytical method) such as selectivity, sensitivity, precision, accuracy and reproducibility. (AU)