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Biomineralization study of diamond-like carbon films containing titanium dioxide nanoparticles

Grant number: 14/11491-8
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2014
Effective date (End): April 30, 2016
Field of knowledge:Engineering - Materials and Metallurgical Engineering - Nonmetallic Materials
Principal Investigator:Fernanda Roberta Marciano
Grantee:Juliana Milani
Host Institution: Instituto de Pesquisa e Desenvolvimento (IP&D). Universidade do Vale do Paraíba (UNIVAP). São José dos Campos , SP, Brazil
Associated research grant:11/20345-7 - Study of nanoparticle-incorporated diamond-like carbon films for biomedical applications, AP.JP
Associated scholarship(s):15/25264-6 - Electrodeposition of hydroxyapatite on 3D surfaces, BE.EP.IC


Nanostructured biomaterials are promising because their similarities with nanostructured components of the extracellular matrix. Diamond-like carbon (DLC) films gather physical and chemical properties such as high hardness, chemical stability, visible transparency, low friction and high resistance to wear. The deposition of hydroxyapatite (HAp) on DLC surface has been studied in order to improve DLC bioactivity, aiming this new composite applicability in bone-regenerative medicine. The aim of this work was to study the in vitro process of HAp/DLC and HAp/TiO2-DLC composites biomineralization, to develop new designs of HAp crystals, seeking to enhance the characteristics and properties of HAp/DLC and HAp/TiO2-DLC composites.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
LOPES, F. S.; OLIVEIRA, J. R.; MILANI, J.; OLIVEIRA, L. D.; MACHADO, J. P. B.; TRAVA-AIROLDI, V. J.; LOBO, A. O.; MARCIANO, F. R.. Biomineralized diamond-like carbon films with incorporated titanium dioxide nanoparticles improved bioactivity properties and reduced biofilm formation. Materials Science & Engineering C-Materials for Biological Applications, v. 81, p. 373-379, . (12/15857-1, 11/17877-7, 11/20345-7, 14/11491-8, 15/09697-0, 16/00575-1)

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