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Synbiotic aerated dessert: diet product development and evaluation of the intake effects in individuals with metabolic syndrome.

Grant number: 13/04422-7
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): May 01, 2014
Effective date (End): May 31, 2017
Field of knowledge:Agronomical Sciences - Food Science and Technology - Food Technology
Principal Investigator:Susana Marta Isay Saad
Grantee:Douglas Xavier dos Santos
Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:13/07914-8 - FoRC - Food Research Center, AP.CEPID


The aim of this study is to adapt a synbiotic aerated diet dessert - a mousse - from the previously developed formulation containing sucrose (BURITI et al., 2010a, b; KOMATSU et al., 2013), prepared with the addition or not (in the case of the control none-synbiotic formulation) of the probiotic Lactobacillus acidophilus La-5 strain and of prebiotic ingredients (inulin and oligofructose) and to evaluate the diet intake effects of the ingestion of this dessert in volunteer adults with metabolic syndrome over a period of 8 weeks of experiment through monitoring clinical, anthropometric, metabolic, and inflammatory parameters. For the product development, the survival of the probiotic culture during its frozen storage at-18 C will be assessed, as well as the counts of micro-organisms indicators of contamination, physico-chemical, instrumental texture and sensory features of the product throughout storage. The synbiotic diet mousse features during storage will be compared to those of the non-synbiotic diet product and to those of the product with sucrose previously developed and that will be produced for this purpose. For the clinical trial, the selected volunteers will be divided into groups of supplementation and placebo group, which will consume, respectively, synbiotic and non-synbiotic mousses. Blood pressure measurements and anthropometric parameters will be determined, besides the collection of blood samples before and after 0 and 8 weeks of intervention with the dairy desserts for the determination of biochemical and inflammatory markers, according to the double-blind placebo controlled experimental design. The results will be analyzed according to the statistical design proposed.

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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
XAVIER-SANTOS, DOUGLAS; BEDANI, RAQUEL; LIMA, EGIDIO DOREA; ISAY SAAD, SUSANA MARTA. Impact of probiotics and prebiotics targeting metabolic syndrome. Journal of Functional Foods, v. 64, . (13/07914-8, 13/04422-7)
XAVIER-SANTOS, DOUGLAS; LIMA, EGIDIO DOREA; COLADO SIMAO, ANDREA NAME; BEDANI, RAQUEL; ISAY SAAD, SUSANA MARTA. Effect of the consumption of a synbiotic diet mousse containing Lactobacillus acidophilus La-5 by individuals with metabolic syndrome: A randomized controlled trial. Journal of Functional Foods, v. 41, p. 55-61, . (13/07914-8, 13/04422-7)
XAVIER-SANTOS, DOUGLAS; BEDANI, RAQUEL; PEREGO, PATRIZIA; CONVERTI, ATTILIO; SAAD, S. M. I.. L-acidophilus La-5, fructo-oligosaccharides and inulin may improve sensory acceptance and texture profile of a synbiotic diet mousse. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 105, p. 329-335, . (13/04422-7, 13/07914-8)
DOS SANTOS, DOUGLAS XAVIER; CASAZZA, ALESSANDRO ALBERTO; ALIAKBARIAN, BAHAR; BEDANI, RAQUEL; ISAY SAAD, SUSANA MARTA; PEREGO, PATRIZIA. Improved probiotic survival to in vitro gastrointestinal stress in a mousse containing Lactobacillus acidophilus La-5 microencapsulated with inulin by spray drying. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 99, p. 404-410, . (13/07914-8, 13/04422-7)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SANTOS, Douglas Xavier dos. Synbiotic aerated dessert: diet product development and evaluation of the intake effects in individuals with metabolic syndrome. 2017. Doctoral Thesis - Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) São Paulo.

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