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Vaccinal profile of dialysis-dependent chronic renal failure population in São Carlos - SP, focus on Hepatitis B vaccine

Grant number: 13/16207-3
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): January 01, 2014
Effective date (End): November 30, 2014
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Sigrid De Sousa dos Santos
Grantee:Maia Nogueira Crown Guimarães
Host Institution: Centro de Ciências Biológicas e da Saúde (CCBS). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil


Considering the need for assessment of the coverage of the National Immunization Program (PNI) in adult patients with dialysis-dependent chronic renal failure and reported cases of hepatitis B infection in hemodialysis units, we propose study to evaluate the hepatitis B serologic markers and vaccination of patients with renal failure requiring dialysis in São Carlos city and region. The study will be conducted at the Serviço de Nefrologia de São Carlos, which provides regular dialysis services for 158 patients coming in São Carlos city and region. Eligible patients will be adults who agree to participate in the study and to sign the informed consent term. Only patients with available vaccine informations will be considered for study. Patients participating will be submitted to interview, review of medical records and vaccination charts. Patients without hepatitis B serologic markers will be referred for collection of the indicated serological markers. Intended that all patients have anti-HBc, anti-HBs and HBsAg tested. Patients whose vaccination charts were not updated will be further referred to the basic health unit for vaccination, and the possible adverse effects of hepatitis B vaccine will be assessed.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MAIA NOGUEIRA CROWN GUIMARÃES; TILA FACINCANI; SIGRID DE SOUSA DOS SANTOS. Situação da hepatite B em pacientes em hemodiálise. Arq. Gastroenterol., v. 54, n. 4, p. 356-358, . (13/16207-3, 13/16215-6)
FACINCANI, TILA; CROWN GUIMARAES, MAIA NOGUEIRA; DOS SANTOS, SIGRID DE SOUSA. Yellow fever vaccination status and safety in hemodialysis patients. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, v. 48, p. 91-95, . (13/16215-6, 13/16207-3)

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