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Grant number: 13/10330-8
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Effective date (Start): September 01, 2013
Effective date (End): December 31, 2015
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal Investigator:Marcelo Jose Strazzeri Bönecker
Grantee:Jenny Haydee Abanto Alvarez
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil


This parallel-group randomized trial proposed to assess the impact of conservative (pulpectomy) versus non-conservative treatment (tooth extraction) for severe dental caries on oral health-related quality of life (OHRQoL) (primary outcome), anthropometric measures, space loss and anxiety of preschool children. The responsiveness of the Brazilian Early Childhood Oral Health Impact Scale (ECOHIS) will be also assessed. One hundred children between 3 and 5 years of age with pufa index >0 in primary molars will be selected along with their parents. Children will be randomly allocated to treatments groups (n= 48 for each group) according to the technique used: (1) pulpectomy, (2) tooth extraction. The Brazilian versions of the ECOHIS and Scale of Oral Health Outcomes for 5-year-old children (SOHO-5) will be used to assess the impact on OHRQoL comparing pre- and post-treatment by total and items scores. Anthropometric measures will be expressed as Z-scores and as conditional growth velocity for BMI-for-age, height-for-age, weight-height and weight-for-age. The extraction space or space occupied by the tooth treated with pulpectomy will be evaluated in millimetres on dental casts. Anxiety will be assessed using the Facial Image Scale before the start of the first treatment session. All the outcomes described above will be evaluated after 4, 8 and 12 months considering the allocation of the treatment groups. The responsiveness of the ECOHIS will be assessed by the magnitude of change total scores in pre- and post-treatment, and parents' global transition judgment. All analyses will be carried out on an intention-to-treat (ITT) basis and considering sensitivity analysis to assess differences between ITT and complete cases analyses.

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Scientific publications (9)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ABANTO, JENNY; VIDIGAL, EVELYN ALVAREZ; CARVALHO, THIAGO SAADS; DE SA, STELLA NUBIA COELHO; BONECKER, MARCELO. Factors for determining dental anxiety in preschool children with severe dental caries. Brazilian Oral Research, v. 31, . (13/10330-8)
ABANTO, JENNY; PAIVA, SAUL MARTINS; SHEIHAM, AUBREY; TSAKOS, GEORGIOS; MENDES, FAUSTO MEDEIROS; CORDESCHI, THAIS; VIDIGAL, EVELYN ALVAREZ; BONECKER, MARCELO. Changes in preschool children's OHRQoL after treatment of dental caries: responsiveness of the B-ECOHIS. International Journal of Paediatric Dentistry, v. 26, n. 4, p. 259-265, . (13/10330-8)
PULACHE, JHONATAN; ABANTO, JENNY; OLIVEIRA, LUCIANA BUTINI; BOENECKER, MARCELO; CESPEDES PORRAS, JACQUELINE. Exploring the association between oral health problems and oral health-related quality of life in Peruvian 11-to 14-year-old children. International Journal of Paediatric Dentistry, v. 26, n. 2, p. 81-90, . (13/10330-8)
ABANTO, JENNY; TSAKOS, GEORGIOS; PAIVA, SAUL MARTINS; CARVALHO, THIAGO S.; RAGGIO, DANIELA P.; BOENECKER, MARCELO. Impact of dental caries and trauma on quality of life among 5-to 6-year-old children: perceptions of parents and children. COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY, v. 42, n. 5, p. 385-394, . (13/10330-8, 09/17040-0)
ABANTO, JENNY; TSAKOS, GEORGIOS; OLEGARIO, ISABEL CRISTINA; PAIVA, SAUL MARTINS; MENDES, FAUSTO MEDEIROS; ARDENGHI, THIAGO MACHADO; BONECKER, MARCELO. Impact of pulpectomy versus tooth extraction in children's oral health-related quality of life: A randomized clinical trial. COMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY, v. N/A, p. 11-pg., . (13/10330-8)
GUSTAVO TELLO; LUCIANA BUTINI OLIVEIRA; CHRISTIANA MURAKAMI; GABRIELA CUNHA BONINI; JENNY ABANTO; MARCELO BÖNECKER. Os desgastes dentários erosivos afetam a qualidade de vida relacionada à saúde bucal em pré-escolares?. RGO - Revista Gaúcha de Odontologia, v. 65, n. 4, p. 326-334, . (11/18412-8, 13/10330-8, 12/00944-6)
TELLO, GUSTAVO; BONINI, GABRIELA CUNHA; MURAKAMI, CHRISTIANA; ABANTO, JENNY; OLIVEIRA, LUCIANA BUTINI; BONECKER, MARCELO. Trends in the prevalence of traumatic crown injuries and associated factors in Brazilian preschool children: 10-year observational data. DENTAL TRAUMATOLOGY, v. 32, n. 4, p. 274-280, . (11/18412-8, 13/10330-8, 12/00944-6)
ABANTO, JENNY; CELIBERTI, PAULA; BRAGA, MARIANA MINATEL; VIDIGAL, EVELYN ALVAREZ; CORDESCHI, THAIS; HADDAD, ANA ESTELA; BOENECKER, MARCELO. Effectiveness of a preventive program based on caries risk assessment and recall intervals on the incidence and regression of initial caries lesions in children. International Journal of Paediatric Dentistry, v. 25, n. 4, p. 291-299, . (13/10330-8)
ABANTO, JENNY; TELLO, GUSTAVO; BONINI, GABRIELA CUNHA; OLIVEIRA, LUCIANA BUTINI; MURAKAMI, CHRISTIANA; BOENECKER, MARCELO. Impact of traumatic dental injuries and malocclusions on quality of life of preschool children: a population-based study. International Journal of Paediatric Dentistry, v. 25, n. 1, p. 18-28, . (11/18412-8, 13/10330-8, 12/00944-6)

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