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Lacases production by marine derived fungi Peniophora sp. CBMAI 1063 on a bench bioreactor

Grant number: 13/12505-0
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): September 01, 2013
Effective date (End): May 31, 2015
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:Lara Durães Sette
Grantee:Pedro Henrique Mainardi
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil


Laccases are multicooper oxidases that catalyzes the oxidation of 4e- of a reduction substrate, with the concomitant reduction of 2e-´of dioxigen to water. These enzymes play a crucial role in the global carbon cycle, having as one of their main application the degradation and neutralization of environmental pollutants. Taking into account the importance of this enzyme in both sectors, biotechnological and environmental, the present work aims to scale-up the production of laccases using the marine-derived basidiomycete Peniophora sp. CBMAI 1063, based on the optimized conditions of production previously obtained in small scale. The laccase produced by the fungus Peniophora sp. CBMAI 1063 has shown significant results in the decolorization of textile dyes.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MAINARDI, PEDRO H.; FEITOSA, VALKER A.; BRENELLI DE PAIVA, LIVIA B.; BONUGLI-SANTOS, RAFAELLA C.; SQUINA, FABIO M.; PESSOA, JR., ADALBERTO; SETTE, LARA D.. Laccase production in bioreactor scale under saline condition by the marine-derived basidiomycete Peniophora sp CBMAI 1063. FUNGAL BIOLOGY, v. 122, n. 5, p. 302-309, . (14/06923-6, 13/12505-0, 13/03061-0, 16/07957-7, 13/19486-0)
BONUGLI-SANTOS, RAFAELLA C.; DOS SANTOS VASCONCELOS, MARIA R.; PASSARINI, MICHEL R. Z.; VIEIRA, GABRIELA A. L.; LOPES, VIVIANE C. P.; MAINARDI, PEDRO H.; DOS SANTOS, JULIANA A.; DUARTE, LIDIA DE AZEVEDO; OTERO, IGOR V. R.; DA SILVA YOSHIDA, ALINE M.; et al. Marine-derived fungi: diversity of enzymes and biotechnological applications. FRONTIERS IN MICROBIOLOGY, v. 6, . (13/00286-1, 08/06720-7, 13/12505-0, 13/08617-7, 11/18769-3, 09/18399-1, 13/19486-0, 12/12622-3)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
MAINARDI, Pedro Henrique. Produção de lacases pelo fungo filamentoso de origem marinha Peniophora sp. CBMAI 1063 em biorreator de bancada. 2015. Master's Dissertation - Universidade Estadual Paulista (Unesp). Instituto de Biociências. Rio Claro Rio Claro.

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