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Human health risk assessment derived from exposure to metals through water and air (PM10) for two population groups (adults and children) in Ribeirão Preto, Brazil

Grant number: 13/50186-3
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): September 01, 2013
Effective date (End): August 31, 2017
Field of knowledge:Health Sciences - Collective Health - Public Health
Principal researcher:Susana Segura Muñoz
Grantee:Renato Igor da Silva Alves
Home Institution: Escola de Enfermagem de Ribeirão Preto (EERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated scholarship(s):16/04457-3 - Comparing the climate change impact on the photodegradation of polycyclic aromatic hydrocarbons (PAHs) in 2 scenarios: São Paulo (Brazil) vs. Catalonia (Spain), BE.EP.PD


Anthropogenic activities can cause the release of large quantities of toxic pollutants into the surface waters, including the heavy metals among them. These toxic pollutants can reach the water and air through various routes and consequently impair the quality of aquatic ecosystems and human health. An effective approach to assess levels of health risk posed by multiple contaminants is the human health risk assessment. There is a clear trend of population growth in the area of Ribeirão Preto and the increase of the economic activities with consequent impacts on water resources, including the Guarani Aquifer System, and air quality. The objective of the present study is to assess the human health risk derived from environmental exposure to metals through water and air for two population groups (adults and children) in Ribeirão Preto, and also assess the levels of metals in air (PM 10), drinking water and groundwater in the study area. Will be assessed the levels of metals in water samples from wells and homes of the city of Ribeirão Preto, and also in air samples (MP10). Metal analysis will be performed by mass inductively coupled plasma spectrometry (ICP-MS, Perkin Elmer Elan 6000). Environmental exposure to metals through water and air will be assessed taking into account a residential scenario in accordance to the methodology set by the Environmental Protection Agency (EPA), and estimated considering the three main routes of exposure: ingestion, dermal contact and inhalation. Also it will be assessed for two population groups: adults and children. Non-carcinogenic and carcinogenic risks will be assessed separately and calculated with the application of Monte Carlo simulation performed by the Crystal Ball software (Decisioneering, Inc., Denver, CO, USA). (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ALVES, RENATO I. S.; MACHADO, CAROLINA S.; BEDA, CASSIO F.; FREGONESI, BRISA M.; NADAL, MARTI; SIERRA, JORDI; DOMINGO, JOSEP L.; SEGURA-MUNOZ, SUSANA I.. Water Quality Assessment of the Pardo River Basin, Brazil: A Multivariate Approach Using Limnological Parameters, Metal Concentrations and Indicator Bacteria. Archives of Environmental Contamination and Toxicology, v. 75, n. 2, p. 199-212, . (13/07238-2, 13/50186-3)
ALVES, RENATO I. S.; MACHADO, GABRIEL P.; ZAGUI, GUILHERME S.; BANDEIRA, OTNIEL A.; SANTOS, V, DANILO; NADAL, MARTI; SIERRA, JORDI; DOMINGO, JOSE L.; SEGURA-MUNOZ, I, SUSANA. Metals risk assessment for children's health in water and particulate matter in a southeastern Brazilian city. Environmental Research, v. 177, . (13/07238-2, 13/50186-3, 16/04457-3)

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