Detection of endocrine disruptors testosterone and estradiol in environmental samples utilizing modified electrodes with graphene, the gold nanoparticles and quantum dots.

Abstract

This project proposes to determine endocrine disruptors (testosterone and estradiol) in environmental samples and clinical. Will develop a methodology for the construction of electrochemical sensors coated glassy carbon nanocomposite-based graphene oxides (GO), gold nanoparticles (NpAu) and CdTe / CdS (quantum dots QDs). The electrode developed (GO / np-Au / QDs) is defined by measurements of atomic force microscopy (AFM), scanning electron microscopy (SEM), X-ray spectroscopy energy dispersive (EDX), and electrochemical techniques (cyclic voltammetry and electrochemical impedance spectroscopy - IEE). We will study the electrochemical behavior of endocrine disruptors in different supporting electrolytes and pH on the surface developed.The sensor developed and optimized allow for increased sensitivity and consequently the determination of endocrine disruptors testosterone and estradiol, with low detection limits. Therefore the sensor is applied to samples of river water and drinking water, industrial and domestic effluents, clinical analysis and sediment extracts. The detection of these interferences occur via oxidation / reduction of the direct electrochemical sensor surface, as much testosterone to estradiol, aiming to develop a system electrocatalytic, precise, sensitive, with potential for miniaturization and possibility of application "in situ" and real time.