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Sensitivity profile of Staphylococcus spp. isolated from bovine mastitis for vancomycin and other antimicrobial agents

Grant number: 12/18607-6
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): November 01, 2012
Effective date (End): October 31, 2013
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Helio Langoni
Grantee:Paula Isabel Trigo Mancilla
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


Mastitis is an inflammation of the mammary gland, responsible for major losses in dairy farming. The genus Staphylococcus has an important role in the etiology of infectious bovine mastitis. Nowadays besides S. aureus, coagulase negative staphylococci (CNS) considered minor, are attracting the interest of researchers due to the risk to public health represented by these micro-organisms in the etiology of mastitis in relation to antimicrobial resistance. The participation of these pathogens in bovine milk by serving and justifies the need to research their antimicrobial resistance. The objectives of this project: to investigate the potential public health risk represented by the resistance of these strains to different antimicrobials, especially vancomycin. Will be studied 150 strains of S. aureus and 150 strains of CNS isolated from cases of bovine mastitis in different properties of the State of São Paulo. The isolates are subjected to profile microbial sensitivity "in vitro" and will be established the minimal inhibitory concentration for vancomycin. Thus this proposal will study the sensitivity profile of samples of S. aureus and SCN against the action of vancomycin. (AU)

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