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Randomized trial to compare two methods for sclerotherapy in reticular veins and telangiectasias in lower limbs

Grant number: 12/12260-4
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2012
Effective date (End): September 30, 2014
Field of knowledge:Health Sciences - Medicine - Surgery
Principal Investigator:MARCONE LIMA SOBREIRA
Grantee:Giovana Piteri Alcantara
Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


The lower limb varicose veins have an estimated overall prevalence of 57.5% of women and 80 to 90% when searching for cosmetic varicose veins among women. Varicose veins are considered the cosmetic frequent complaints in the office of Angiologist and Vascular Surgeon and are a feature, not present pain. There are numerous techniques for treating varicose veins aesthetic, among the most common, including the chemical sclerotherapy which aims to endothelial injury and obliteration of the vessels sclerotic. To reticular varicose veins, there is no consensus and there are few publications on the treatment escleroterápico alternative to surgical procedure, which justifies this work. Objective: To evaluate two methods of chemical sclerotherapy as a treatment for telangiectasias and reticular veins in the lower limbs in objective and subjective quantification by photos. It will be also assessed the safety of methods for the occurrence of adverse events. Methods: Prospective, controlled, randomized, double-blind. The sample of convenience will be continued. This will include 200 legs randomized independently. The treatment area was defined as the posterior knee limited by anatomically rectangle: 25cm and 5cm planting row after tibial crest width of 10cm and 40cm length (area 400cm2) using the square of patterned paper. The treatment will be performed in a single session in the designated area to eliminate all reticular veins and telangiectasias. The area is imaged and re-evaluated quantitatively on days 0, 21, and 60 after application. The quantification is made with a square of plastic with circular marks of 2mm diameter, equidistant 3mm. Will be undertaken in the statistical analysis of results.(AU)

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