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Nanotechnology in farming: use of a nanopropolis formulation as a therapeutical alternative for bovine mastitis control in organic dairy farms

Grant number: 12/03212-6
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Effective date (Start): October 01, 2012
Effective date (End): September 30, 2014
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Helio Langoni
Grantee:Marcella Zampoli Troncarelli
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


Organic dairy farms are supposed to use only phytotherapeutical and homeaopatical actives for mastitis control in cows. However, there is a low number of actives available for this application. Considering the bactericide action of the propolis and the fact that this substance is allowed in organic dairy farms, Brazilian researches developed the nanoestructured propolis, a promissor poduct for intramamary treatment against mastitis. It is expected that this nanostructure presents better antimicrobial effects and lower irritability for mammary glands, considering that the previous in vitro studies done against bacterial reference strains showed excellent results. For in vivo studies it was established an important partnership between EMBRAPA Dairy Farm (who will provide the nanostructures batches) and FMVZ-UNESP/Botucatu-SP (who will apply the product in cows and will also conduct clinical and laboratorial evaluations). The aim of the present study is to evaluate the safety and efficacy of a nanoestructured propolis formulation produced by EMBRAPA Dairy Farm (MG) in dairy organic farms sited in Botucatu-SP and region. If the expectations regarding the safety and efficacy of the nanoestructured propolis be confirmed, the patented final formulation may be directed for industrial production, especially attending the demands of dairy farms organic systems. (AU)

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