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Study of laminitis in sheep with ruminal lactic acidosis experimentally induced

Grant number: 12/09111-7
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): September 01, 2012
Effective date (End): August 31, 2015
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal Investigator:Luiz Carlos Marques
Grantee:Annita Morais Girardi
Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


The sheep industry for meat production is rising in Brazil and this causes increase in the number of confined animals, aiming bigger weight gain in a shorter time. This situation predisposes sheeps to disorders like ruminal lactic acidosis and, consequently, laminitis, that generate economic losses due to treatment costs, lower productivity of the herd, discard of animals, besides affecting adversely the welfare of them. In this respect, the developing of more trustworthy diagnostic methods, able to identify this disease at an early evolutionary stage can help in a faster and more efficient prophylaxis, thus, minimizing economic losses. This study aims to verify the efficacy of infrared thermography and radiological evaluation as early diagnostic tools of laminitis in sheeps with rumenal lactic acidosis experimentally induced. It will also be evaluated the alterations in hemogasometry, plasmatic glucose and lactate levels, urinary pH, ruminal fluid parameters and eletrophoretic profile of serum proteins.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GIRARDI, ANNITA MORAIS; SABES, AMANDA FESTA; FAGLIARI, JOSE JURANDIR; DA SILVA, PAULO CESAR; DE OLIVEIRA, JOAO ADEMIR; MARQUES, LUIZ CARLOS. Changes in the levels of acute-phase protein and other serum protein fractions in Santa Ines ewes fed with a high-concentrate diet. Small Ruminant Research, v. 162, p. 34-38, . (12/09111-7, 12/09220-0)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
GIRARDI, Annita Morais. Subacute ruminal acidosis in sheep: clinical-laboratory study, and laminitis evaluation through infrared termography and digital radiology. 2016. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.

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