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BETA TRICALCIUM PHOSPHATE in maxillary membrane sinus lifting. Histological, histomorphometric and immunohistochemistry study in rabbits.

Grant number: 12/13812-0
Support type:Scholarships in Brazil - Master
Effective date (Start): September 01, 2012
Effective date (End): August 31, 2014
Field of knowledge:Health Sciences - Dentistry - Oral and Maxillofacial Surgery
Principal researcher:Elio Hitoshi Shinohara
Grantee:Patricia Rota Bermejo
Home Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil


The beta tri calcium phosphate (²-TCP) is a biomaterial with excellent osteoconductive properties, biocompatibility by being chemically and crystallographically similar to the human bone tissue as well as having rapid reabsorption which reduces biological reactions. The ²-TCP has been used in bone grafting surgery, especially in the upper regions of the maxilla in order to facilitate the prosthetic rehabilitation with implants. The aim of this study is to evaluate the healing of a biomaterial-based beta tri calcium phosphate, ²-TC in sinus lifting of rabbits, using histological, histomorphometric and immunohistochemistry. Will be used twenty (20) rabbits Albinus who will submit to bilateral sinus lifting surgery surgery. The right maxillary sinus will be filled by clot and the left by ²-TCP. After periods of 3, 7, 14 and 40 days the animals will suffer euthanasia and maxilla is removed for processing and histological, immunohistochemical and histometric. Statistical analysis will be conducted through the comparison between control and treated group. The statistical test used depends on the distribution of these data in relation to normal values.

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
BERMEJO, Patricia Rota. Uso do beta fosfato tricálcio em levantamento da membrana de seio maxilar: estudo histológico, histomorfométrico e imunoistoquímico em coelhos. 2014. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Odontologia. Araçatuba Araçatuba.

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