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Synthesis, characterization and biological assay of metallic chelates containing natural ligands

Grant number: 12/15639-4
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2012
Effective date (End): September 30, 2013
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
Principal Investigator:Regina Celia Galvao Frem
Grantee:Aline Renata Pavan
Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil


This work deals with the synthesis and characterization of Pd(II), Pt(II), and Ag(I) compounds containing hydrolyzed proteins of bovine milk serum or egg white as well citric pectin. The idea consists of preparing metallic chelates containing natural ligands to use as antimicrobial or anticancer drugs. Besides that, the milk serum, a proteic subproduct from the lacticínio industry, has been inadvertently discarded in rivers carrying out serious ambient risks. This project will have the collaboration of Profs. R. Monti, T. M. Bauab and I. Z. Carlos of FCF-UNESP as well Profs. Adelino V. G. Netto and E. Maffud of this Institute.(AU)

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