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Polysomnographic and cephalometric study in children with obstructive sleep apnea syndrome (OSA).

Grant number: 12/00092-0
Support Opportunities:Scholarships in Brazil - Post-Doctorate
Effective date (Start): September 01, 2012
Effective date (End): August 31, 2015
Field of knowledge:Health Sciences - Medicine
Principal Investigator:Agrício Nubiato Crespo
Grantee:Almiro José Machado Júnior
Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil


With the evolution of species and the complex physiological and anatomical sophisticated living organisms, human beings represent the culmination of this complexity. With the improvement of mechanisms for maintaining life, also develop the disease. Among the modern diseases, the syndrome obstructive sleep apnea (OSA) has recently been the object of several studies, although since the remotest times, sleep wake great scientific interest. This syndrome is a chronic, progressive, with high morbidity and mortality, with a set symptomatic polymorphic ranging from snoring to excessive sleepiness daytime, with serious repercussions general hemodynamic and neurological behavior. Currently numerous studies have been conducted in order to highlight anatomical abnormalities that predispose to OSA adult patients. Several additional tests have been used in complementary diagnosis of this syndrome. Cephalometric examination in lateral radiograph of the face has been widely used in these studies. However there are few studies using this method in a pediatric population, where the problem can perhaps be diagnosed and treated early. Therefore, the purpose of this study is evaluate and correlate, by means of lateral cephalometric, probable anatomical changes in a group of children with OSA, propose and evaluate the use of maxillomandibular device for the treatment of this syndrome, assess and correlate polysomnographic data pre and post treatment and to correlate our data to study data previous child with a sample orofacial myology disorder.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MACHADO-JUNIOR, ALMIRO-JOSE; ZANCANELLA, EDILSON; CRESPO, AGRICIO-NUBIATO. Rapid maxillary expansion and obstructive sleep apnea: A review and meta-analysis. MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, v. 21, n. 4, p. E465-E469, . (12/00092-0)
MACHADO-JUNIOR, ALMIRO-JOSE; SIGNORELLI, LUIZ-GABRIEL; ZANCANELLA, EDILSON; CRESPO, AGRICIO-NUBIATO. Randomized controlled study of a mandibular advancement appliance for the treatment of obstructive sleep apnea in children: A pilot study. MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL, v. 21, n. 4, p. E403-E407, . (12/00092-0)

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