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Development of biosensors nanostructured based biointerface nanowires/enzymes

Grant number: 12/01402-2
Support type:Scholarships in Brazil - Master
Effective date (Start): August 01, 2012
Effective date (End): January 31, 2014
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Principal researcher:Valber de Albuquerque Pedrosa
Grantee:Gislaine Passarella Gerola
Home Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil


This proposal is aimed at development of nanowires for biosensors application. Currently, nanotechnology field has been highlighted by the extreme sensitivity of biosensor based nanowires. As they have virtually the same size as the molecules that are detected, these nanosensors could revolutionize the diagnoses way are made in medical and biological. The first studies will focus on production and characterization of multi-segmented nanowires using different metals (nickel, silver, gold) and polymers (pyrrole), which will be made by the electrochemical deposition process. The nanowires will be characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The next step will be studied further alternative for the immobilization of enzymes for preparing biosensors. The fabricated devices will be used for the direct determination of glucose. Thus, it is expected to obtain a methodology less costly and time of analysis.

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Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
GEROLA, Gislaine Passarella. Utilização da biointerface nanofios/enzimas para o desenvolvimento de biossensores nanoestruturados. 2014. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências. Bauru Bauru.

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