| Grant number: | 11/22611-6 |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| Effective date (Start): | March 01, 2012 |
| Effective date (End): | February 28, 2017 |
| Field of knowledge: | Biological Sciences - Biochemistry - Molecular Biology |
| Principal Investigator: | Bettina Malnic |
| Grantee: | João Batista Placido do Nascimento |
| Host Institution: | Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated research grant: | 07/50743-9 - G protein coupled receptors and chemosensation, AP.TEM |
Abstract Mammals can discriminate a vast number of odorants through their sense of smell. In the nasal cavity there are millions of olfactory sensory neurons, which are involved in this task. Odorants activate odorant receptors expressed in the cilia of olfactory neurons. The Odorant Receptors (ORs) belong to the GPCR superfamily and constitute a large gene family composed of around 1000 members in mice. Each olfactory neuron expresses one single type of OR gene, while the remaining OR genes remain silent. In this project we plan to investigate wether non codig RNAs are involved in the regulation of OR gene expression. (AU) | |
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