Scholarship 11/18174-0 - Resposta inflamatória, Tithonia diversifolia - BV FAPESP
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Study of the immunomodulatory activities of Tithonia diversifolia in human neutrophils.

Grant number: 11/18174-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date until: January 01, 2012
End date until: December 31, 2012
Field of knowledge:Biological Sciences - Immunology - Applied Immunology
Principal Investigator:Ana Paula Campanelli
Grantee:Aneli Eiko Abe
Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

The immunomodulatory activity of several medicinal plants from the family Asteraceae is due to the presence of sesquiterpene lactones. The immunomodulatory activity of the Tithonia diversifolia in human neutrophils will be investigated. Methods and Results: Neutrophils will be cultured with fMLP or budlein A for 18h and cytokines production analyzed by ELISA.

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ABE, ANELI E.; DE OLIVEIRA, CARINE E.; DALBONI, THALITA M.; CHAGAS-PAULA, DANIELA A.; ROCHA, BRUNO A.; DE OLIVEIRA, REJANE B.; GASPAROTO, THAIS H.; DA COSTA, FERNANDO B.; CAMPANELLI, ANA P.. Anti-inflammatory sesquiterpene lactones from Tithonia diversifolia trigger different effects on human neutrophils. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 25, n. 2, p. 111-116, . (08/02185-0, 11/01862-0, 11/18174-0, 09/14127-7, 10/10940-2, 10/19317-6)

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