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Investigation of the secondary metabolism of two fungal strains from the marine environment

Grant number: 11/08064-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2011
Effective date (End): June 30, 2013
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Roberto Gomes de Souza Berlinck
Grantee:Laura Pavan Ióca
Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil

Abstract

The present investigation aims to obtain knowledge on the secondary metabolism of two fungal strains, isolated from an ascidian, Didemnum ligulum. After strains growth in artificial media and obtention of the respective crude extracts, separation steps will be performed in order to isolate pure compounds to be identified using spectroscopic techniques. The biological activity of the isolated compounds will be evaluated in the same assays in which crude extracts presented activity. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
LAURA P. IÓCA; STELAMAR ROMMINGER; MARIO F. C. SANTOS; KARIN F. BANDEIRA; FABIANA T. RODRIGUES; MIRIAM H. KOSSUGA; KAREN J. NICACIO; EVERTON L. F. FERREIRA; RAQUEL P. MORAIS-URANO; MESSIAS S. PASSOS; et al. A STRATEGY FOR THE RAPID IDENTIFICATION OF FUNGAL METABOLITES AND THE DISCOVERY OF THE ANTIVIRAL ACTIVITY OF PYRENOCINE A AND HARZIANOPYRIDONE. Química Nova, v. 39, n. 6, p. 720-731, . (11/08064-2, 10/50190-2, 13/23153-7, 13/50228-8, 08/00331-9)
IOCA, LAURA P.; ALLARD, PIERRE-MARIE; BERLINCK, ROBERTO G. S.. Thinking big about small beings - the (yet) underdeveloped microbial natural products chemistry in Brazil. NATURAL PRODUCT REPORTS, v. 31, n. 5, p. 646-675, . (11/08064-2, 10/50190-2, 12/04100-7)
GALLAGHER, KELLEY A.; RAUSCHER, KRISTIN; IOCA, LAURA PAVAN; JENSEN, PAUL R.. Phylogenetic and Chemical Diversity of a Hybrid-IsoprenoidProducing Streptomycete Lineage. Applied and Environmental Microbiology, v. 79, n. 22, p. 6894-6902, . (11/08064-2)

Please report errors in scientific publications list by writing to: gei-bv@fapesp.br.