Advanced search
Start date

Research about the impact of neuropsychological rehabilitation on cocaine/crack dependents

Grant number: 10/01272-6
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): August 01, 2011
Effective date (End): April 30, 2012
Field of knowledge:Humanities - Psychology
Principal Investigator:Arthur Guerra de Andrade
Grantee:Priscila Dib Goncalves
Host Institution: Instituto de Psiquiatria Doutor Antonio Carlos Pacheco e Silva (IPq). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil


Cocaine/Crack Dependence has been associated with neuropsychological impairments mainly in executive functions and decision-making, which are predominantly managed by the prefrontal cortex (PFC) in the brain. However, none study in Neuropsychological Rehabilitation (NR) has been done in order to remediate the executive functioning in this population. The aim of this research is to investigate the impact of neuropsychological intervention based on the stimulation of cognitive functions such as attention, planning, organization, logical reasoning, executive functioning, and decision making. For this research it will be proposed interventions through motivational strategies and board games, especially chess because it has been associated with PFC functioning, since it is a game which requires complex cognitive abilities, such as: inhibitory control, mental flexibility, sustained attention, future planning and decision-making. There will be two groups of patients with cocaine/crack dependence (n = 56), one with NR (group A, n = 28) and another without NR (group B, n = 28). Group B will be submitted to the placebo intervention. Both groups will be submitted to an extensive battery of neuropsychological tests, before and after interventions. The hypothesis is that group A will present a pronounced improvement on the neuropsychological test compared to group B. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (5)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
OLIVEIRA, HERCILIO P.; GONCALVES, PRISCILA D.; OMETTO, MARIELLA; SANTOS, BERNARDO; MALBERGIER, ANDRE; AMARAL, RICARDO; NICASTRI, SERGIO; ANDRADE, ARTHUR G.; CUNHA, PAULO J.. The Route of Administration Exacerbates Prefrontal Functional Impairments in Crack Cocaine Users. PSYCHOLOGY OF ADDICTIVE BEHAVIORS, v. 32, n. 7, p. 812-820, . (11/19179-5, 10/01272-6, 10/15604-0)
GONCALVES, PRISCILA DIB; OMETTO, MARIELLA; BECHARA, ANTOINE; MALBERGIER, ANDRE; AMARAL, RICARDO; NICASTRI, SERGIO; MARTINS, PAULA A.; BERALDO, LIVIA; DOS SANTOS, BERNARDO; FUENTES, DANIEL; et al. Motivational Interviewing combined with chess accelerates improvement in executive functions in cocaine dependent patients: A one-month prospective study. DRUG AND ALCOHOL DEPENDENCE, v. 141, p. 79-84, . (10/01272-6)
DE OLIVEIRA JUNIOR, HERCILIO PEREIRA; DI GONCALVES, PRISCILA; OMETTO, MARIELLA; DOS SANTOS, BERNARDO; MALBERGIER, ANDRE; AMARAL, RICARDO; NICASTRI, SERGIO; DE ANDRADE, ARTHUR GUERRA; CUNHA, PAULO JANNUZZI. Distinct effects of cocaine and cocaine plus cannabis on neurocognitive functioning and abstinence: A six-month follow-up study. DRUG AND ALCOHOL DEPENDENCE, v. 205, . (11/19179-5, 10/01272-6, 10/15604-0)
LIM, DANIELLE RUIZ; GONCALVES, PRISCILA DIB; OMETTO, MARIELLA; MALBERGIER, ANDRE; AMARAL, RICARDO ABRANTES; DOS SANTOS, BERNARDO; CAVALLET, MIKAEL; CHAIM-AVANCINI, TIFFANY; SERPA, MAURICIO HENRIQUES; KOBUTI FERREIRA, LUIZ ROBERTO; et al. The role of neurocognitive functioning, substance use variables and the DSM-5 severity scale in cocaine relapse: A prospective study. DRUG AND ALCOHOL DEPENDENCE, v. 197, p. 255-261, . (10/15786-1, 10/15604-0, 10/01272-6)
LOPES, BRUNA MAYARA; GONCALVES, PRISCILA DIB; OMETTO, MARIELLA; DOS SANTOS, BERNARDO; CAVALLET, MIKAEL; CHAIM-AVANCINI, TIFFANY MOUKBEL; SERPA, MAURICIO HENRIQUES; NICASTRI, SERGIO; MALBERGIER, ANDRE; BUSATTO, GERALDO F.; et al. Distinct cognitive performance and patterns of drug use among early and late onset cocaine users. ADDICTIVE BEHAVIORS, v. 73, p. 41-47, . (10/15604-0, 10/01272-6, 11/19179-5, 11/09946-9)

Please report errors in scientific publications list by writing to: