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Influence of Black tea from Camellia sinensis plant in the reproduction of superovulated Wistar rats.

Grant number: 10/20274-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2011
Effective date (End): April 30, 2012
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Reproduction
Principal researcher:Ines Cristina Giometti Ceda
Grantee:Erica Solange Caetano Kikuchi
Home Institution: Faculdade de Ciências Agrárias. Universidade do Oeste Paulista (UNOESTE). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil


The female reproductive organs are always growing and regressing. Because of that, they suffer continually remarkable changes in the degree of blood flow. So they are some of the few adult tissues in which the angiogenesis occurs as a normal process. Ovarian follicles and corpus luteum contain and produce angiogenic factors. The main angiogenic factors are the vascular endothelial growth factors (VEGFs). Studies show that some catechins in the Black tea inhibit the VEGFs, but there are no studies demonstrating that the chronic consumption of Black tea can interfere with reproduction. The aim of this study is to determine the influence of Black tea in ovulation rate in superovulated rats by the number of corpus luteum and ovarian weight. For this, the rats will be divided into two groups: control group (n = 30) and group that will intake the Black tea (n = 30). The corpus luteum will be collected from 10 animals in each group at the end of each month, for three consecutive months, the number of corpora lutea and ovarian weight will be assessed. The statistical comparisons will be submitted to unpaired t test realized and the variance analysis for parametric variables, and Mann-Whitney and Kruskal-Wallis tests for variables that are not parametric, differences will be considered when p<0.05.

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