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Study of the antioxidant activity mechanism of Baccharis dracunculifolia(Asteraceae) in neutrophils and evaluation of this effect on rheumatoid arthritis model

Grant number: 10/19504-0
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): May 01, 2011
Effective date (End): June 30, 2015
Field of knowledge:Health Sciences - Pharmacy - Pharmacognosy
Principal Investigator:Yara Maria Lucisano Valim
Grantee:Andréa Silva Garcia de Figueiredo Rinhel
Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
News published in Agência FAPESP Newsletter about the scholarship:
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VEICULO: TITULO (DATA)

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ANDRADE, MICASSIO F.; KABEYA, LUCIANA M.; BORTOT, LEANDRO O.; DOS SANTOS, GABRIELA B.; SANTOS, EVERTON O. L.; ALBIERO, LUCINEIA R.; FIGUEIREDO-RINHEL, ANDREA S. G.; CARVALHO, CAMILA A.; AZZOLINI, ANA ELISA C. S.; CALIRI, ANTONIO; et al. The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3 `,4 `-methylenedioxyphenyl]-coumarin downmodulates the Fc gamma R- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps. Free Radical Biology and Medicine, v. 115, p. 421-435, . (13/20810-7, 13/00927-7, 10/19504-0, 12/23541-4)
FIGUEIREDO-RINHEL, ANDREA S. G.; DE MELO, LAMARTINE L.; BORTOT, LEANDRO O.; SANTOS, EVERTON O. L.; ANDRADE, MICASSIO F.; AZZOLINI, ANA ELISA C. S.; KABEYA, LUCIANA M.; CALIRI, ANTONIO; BASTOS, JAIRO K.; LUCISANO-VALIM, YARA MARIA. Baccharis dracunculifolia DC (Asteraceae) selectively modulates the effector functions of human neutrophils. Journal of Pharmacy and Pharmacology, v. 69, n. 12, p. 1829-1845, . (12/23541-4, 10/19504-0, 13/20810-7, 13/00927-7)
GARCIA DE FIGUEIREDO-RINHEL, ANDREA SILVA; DE ANDRADE, MICASSIO FERNANDES; LANDI-LIBRANDI, ANA PAULA; CALEIRO SEIXAS AZZOLINI, ANA ELISA; KABEYA, LUCIANA MARIKO; BASTOS, JAIRO KENUPP; LUCISANO-VALIM, YARA MARIA. Incorporation of Baccharis dracunculifolia DC (Asteraceae) leaf extract into phosphatidylcholine-cholesterol liposomes improves its anti-inflammatory effect in vivo. NATURAL PRODUCT RESEARCH, v. 33, n. 17, p. 2521-2525, . (12/23541-4, 10/19504-0, 13/20810-7, 13/00927-7)
ANDRADE, MICASSIO F.; KABEYA, LUCIANA M.; BORTOT, LEANDRO O.; DOS SANTOS, GABRIELA B.; SANTOS, EVERTON O. L.; ALBIERO, LUCINEIA R.; FIGUEIREDO-RINHEL, ANDREA S. G.; CARVALHO, CAMILA A.; AZZOLINI, ANA ELISA C. S.; CALIRI, ANTONIO; et al. The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3 ',4 '-methylenedioxyphenyl]-coumarin downmodulates the Fc gamma R- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation and release of neutrophil extracellular traps. Free Radical Biology and Medicine, v. 115, p. 15-pg., . (10/19504-0, 12/23541-4, 13/20810-7, 13/00927-7)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
RINHEL, Andréa Silva Garcia de Figueiredo. Ethanolic extract of Baccharis dracunculifolia (Asteraceae) leaves modulates neutrophil effector functions: a promising herbal agent for the treatment of inflammatory processes mediated by these cells. 2015. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (PCARP/BC) Ribeirão Preto.

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