Brachytherapy is radiotherapy modality, which insert radioactive sources into patient cavities or surgically to treat lung, cervix, prostate and several others types of cancer. One of its main advantages is the capability to deliver high dose to the tumor while preserving adjacent tissues with results equivalents, or even better, than teletherapy. Modern brachytherapy with 3D treatment planning systems (TPS) and remote afterloaders are now possible due to several technological advances and a good clinical outcome. However, there are no protocols that correlate the dose into the tumor volume, organs at risk and/or prescription points (e.g. Point A from ICRU38). Several international studies are aiming to correlate dose-volume using 3D TPS and medical images, as magnetic image resonance. This project aims to aid two hospitals (Brazilian and Dutch) members of the EMBRACE project that are moving to 3D planning. Commercial TPS were compared against Monte Carlo codes and treatments complexities evaluated to obtain more accurate dose distributions to the tumor and organs at risk. These results associated with source parameters and motion can lead to dose-volume calculation methodologies that are more accurate and its relation with previous treatment protocols.
News published in Agência FAPESP Newsletter about the scholarship: