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Effect of periodontal treatment on the lipid profile of obese patients with chronic periodontitis.

Grant number: 10/17614-3
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2011
Effective date (End): December 31, 2011
Field of knowledge:Health Sciences - Dentistry - Periodontology
Principal Investigator:Elizangela Partata Zuza
Grantee:Mariana Fabricio
Host Institution: Centro Universitário da Fundação Educacional de Barretos (UNIFEB). Fundação Educacional de Barretos (FEBA). Barretos , SP, Brazil


Studies have been showed that the hyperlipidemia is associated to the periodontal disease and that the obesity can affect even more the dislipidemy levels, increasing the total cholesterol, triglycerides and low-density lipoprotein cholesterol. There are evidences that the periodontal treatment may improve metabolic control of hyperlipidemia. The aim of this study will be to evaluate the effect of nonsurgical periodontal treatment on lipid profile in obese patients with chronic periodontitis. Patients will be divided into two groups: group 1 - Obese with chronic periodontitis (n = 25) and group 2 - normal weight with chronic periodontitis (n = 25). The following clinical periodontal parameters will be evaluated: plaque index (VPI), bleeding index (GBI), gingival recession (GR), probing depth (PD) and clinical attachment level (CAL). Blood samples will be collected to verify the lipid profile of patients, analyzing the levels of triglycerides, total cholesterol, high-density lipoprotein (HDL) and low-density lipoprotein (LDL). The non-surgical periodontal treatment will be performed in both groups and the periodontal parameters and lipid levels will be assessed before and 3 months after the completion of periodontal treatment. The statistical analysis will be performed considering the normality of the data, with a significance level of 5%.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
ZUZA, ELIZANGELA P.; BARROSO, ELIANE M.; FABRICIO, MARIANA; CARRARETO, ANA LUIZA V.; TOLEDO, BENEDICTO E. C.; PIRES, JULIANA R.. Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy. JOURNAL OF ORAL SCIENCE, v. 58, n. 3, p. 423-430, . (10/17614-3)

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