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Design of inhibitors for dihydroorotate dehydrogenase from Trypanosoma cruzi and Leishmania major

Grant number: 07/08703-0
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2008
Effective date (End): February 29, 2012
Field of knowledge:Biological Sciences - Biophysics - Molecular Biophysics
Principal Investigator:Maria Cristina Nonato
Grantee:Matheus Pinto Pinheiro
Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
REIS, RENATA A. G.; CALIL, FELIPE ANTUNES; FELICIANO, PATRICIA ROSA; PINHEIRO, MATHEUS PINTO; NONATO, M. CRISTINA. The dihydroorotate dehydrogenases: Past and present. Archives of Biochemistry and Biophysics, v. 632, n. SI, p. 175-191, . (11/23504-9, 07/08703-0, 12/25075-0)
PADUA, RICARDO A. P.; TOMALERI, GIOVANI P.; REIS, RENATA A. G.; DAVID, JULIANA S.; SILVA, VALERIA C.; PINHEIRO, MATHEUS P.; NONATO, MARIA CRISTINA. ThermoFMN - a thermofluor assay developed for ligand-screening as an alternative strategy for drug discovery. Journal of the Brazilian Chemical Society, v. 25, n. 10, p. 1864+, . (11/23504-9, 07/08703-0, 08/11644-8, 11/14269-6, 12/25075-0)
REIS, RENATA A. G.; CALIL, FELIPE ANTUNES; FELICIANO, PATRICIA ROSA; PINHEIRO, MATHEUS PINTO; NONATO, M. CRISTINA. The dihydroorotate dehydrogenases: Past and present. Archives of Biochemistry and Biophysics, v. 632, p. 17-pg., . (12/25075-0, 11/23504-9, 07/08703-0)
PINHEIRO, MATHEUS PINTO; EMERY, FLAVIO DA SILVA; CRISTINA NONATO, M.. Target Sites for the Design of Anti-trypanosomatid Drugs Based on the Structure of Dihydroorotate Dehydrogenase. CURRENT PHARMACEUTICAL DESIGN, v. 19, n. 14, p. 2615-2627, . (09/14184-0, 07/08703-0)

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