Research Grants 17/09550-4 - Ressonância magnética, Diagnóstico por imagem - BV FAPESP
Advanced search
Start date
Betweenand

Investigation of feasibility to use computer aided texture analysis for detection and classification of ameloblastomas and keratocysts

Abstract

Imaging assessments have become a fundamental part of biomedical sciences, not only for diagnosis, but also for planning, treatment and follow-up in health sciences. The development of digital image analysis technologies has made possible to increase the sensitivity and specificity of these investigations. Texture analysis is one of them. Through this analysis it is possible to describe, by means of statistical parameters, if there are differences between tissues of different examined regions, as well as between healthy tissues and affected by pathologies, in the same region, having the ability to detect image patterns that are normally imperceptible to human vision.Ameloblastoma and keratocystic are benign odontogenic lesions that develop from epithelial remains of structures involved in dental development. The differential diagnosis between these two lesions and their clinical/pathological subtypes remains a challenge due to their morphological similarities, which hinder differentiation. Magnetic resonance imaging (MRI) is one of imaging exams for the analysis of both lesions.This project aims to investigate whether texture analysis of MR images can add important information on the differentiation of different types of ameloblastomas and keratocysts. For this, patients with both lesions will be selected. We will perform the image textural analysis with the Matlab software, selecting suitable textural analysis parameters and verifying their validity in imaging and histopathological diagnosis and molecular profile of ameloblastomas, regarding the BRAF V600E mutation and a non-coding RNAs panel (by deep sequencing analysis). We will correlate the image changes with the progression of the clinical, histopathological, molecular and morphometric parameters. Subsequently, it will be evaluated if these texture parameters are able to predict if the lesion is in agreement with the final histological diagnosis and molecular profile. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
More itemsLess items
Articles published in other media outlets ( ):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (11)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
COSTA, A. L. F.; CARREIRA, B. DE SOUZA; FARDIM, K. A. C.; NUSSI, A. D.; DA SILVA LIMA, V. C.; MIGUEL, V, M. M.; JARDINI, M. A. N.; SANTAMARIA, M. P.; DE CASTRO LOPES, S. L. P.. Texture analysis of cone beam computed tomography images reveals dental implant stability. International Journal of Oral and Maxillofacial Surgery, v. 50, n. 12, p. 1609-1616, . (17/09550-4, 19/10675-1)
PEREZ GOMES, JOAO PEDRO; CASTRO VELOSO, JOSE DE RIBAMAR; ALTEMANI, ALBINA MESSIAS DE ALMEIDA M.; CHONE, CARLOS TAKAHIRO; CARRASCO ALTEMANI, JOAO MAURICIO; DE FREITAS, CLAUDIO FROES; PASSOS LIMA, CARMEN SILVIA; BRAZ-SILVA, PAULO HENRIQUE; FERREIRA COSTA, ANDRE LUIZ. Three-Dimensional Volume Imaging to Increase the Accuracy of Surgical Management in a Case of Recurrent Chordoma of the Clivus. AMERICAN JOURNAL OF CASE REPORTS, v. 19, p. 1168-1174, . (17/09550-4)
DE ROSA, CATHARINA SIMIONI; BERGAMINI, MARIANA LOBO; PALMIERI, MICHELLE; DE SANTANA SARMENTO, DMITRY JOSE; DE CARVALHO, MARCIA OLIVEIRA; FRANCO RICARDO, ANA LUCIA; HASSEUS, BENGT; JONASSON, PETER; BRAZ-SILVA, PAULO HENRIQUE; FERREIRA COSTA, ANDRE LUIZ. Differentiation of periapical granuloma from radicular cyst using cone beam computed tomography images texture analysis. HELIYON, v. 6, n. 10, . (17/09550-4, 09/53982-0)
SANTOS, WELLINGTON PEREIRA DOS; GOMES, JOAO PEDRO PEREZ; NUSSI, AMANDA DRUMSTAS; ALTEMANI, JOAO MAURICIO; DOS SANTOS, MARIA TERESA BOTTI RODRIGUES; HASSEUS, BENGT; GIGLIO, DANIEL; BRAZ-SILVA, PAULO HENRIQUE; COSTA, ANDRE LUIZ FERREIRA. Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors. INTERNATIONAL JOURNAL OF DENTISTRY, v. 2020, . (17/09550-4)
NUSSI, AMANDA DRUMSTAS; DE CASTRO LOPES, SERGIO LUCIO PEREIRA; DE ROSA, CATHARINA SIMIONI; GOMES, JOAO PEDRO PEREZ; OGAWA, CELSO MASSAHIRO; BRAZ-SILVA, PAULO HENRIQUE; COSTA, ANDRE LUIZ FERREIRA. In vivo study of cone beam computed tomography texture analysis of mandibular condyle and its correlation with gender and age. Oral Radiology, v. 39, n. 1, p. 7-pg., . (17/09550-4, 19/00495-6)
GOMES, JOAO PEDRO PEREZ; OGAWA, CELSO MASSAHIRO; SILVEIRA, RAFAEL V.; CASTELLANO, GABRIELA; DE ROSA, CATHARINA SIMIONI; YASUDA, CLARISSA LIN; ROCHA, ANDRE CAROLI; HASSEUS, BENGT; ORHAN, KAAN; BRAZ-SILVA, PAULO HENRIQUE; et al. Magnetic resonance imaging texture analysis to differentiate ameloblastoma from odontogenic keratocyst. SCIENTIFIC REPORTS, v. 12, n. 1, p. 9-pg., . (17/09550-4, 13/07559-3)
FERREIRA COSTA, ANDRE LUIZ; PAIXAO, ALINE KATAKI; GONCALVES, BIANCA COSTA; OGAWA, CELSO MASSAHIRO; MARTINELLI, THIAGO; MAEDA, FERNANDO AKIO; TRIVINO, TARCILA; PEREIRA DE CASTRO LOPES, SERGIO LUCIO. Cone Beam Computed Tomography-Based Anatomical Assessment of the Olfactory Fossa. INTERNATIONAL JOURNAL OF DENTISTRY, v. 2019, p. 7-pg., . (17/09550-4)
FERREIRA COSTA, ANDRE LUIZ; PAIXAO, ALINE KATAKI; GONCALVES, BIANCA COSTA; OGAWA, CELSO MASSAHIRO; MARTINELLI, THIAGO; MAEDA, FERNANDO AKIO; TRIVINO, TARCILA; PEREIRA DE CASTRO LOPES, SERGIO LUCIO. Cone Beam Computed Tomography-Based Anatomical Assessment of the Olfactory Fossa. INTERNATIONAL JOURNAL OF DENTISTRY, . (17/09550-4)
GONCALVES, BIANCA C.; DE ARAUJO, ELAINE C.; NUSSI, AMANDA D.; BECHARA, NAIRA; SARMENTO, DMITRY; OLIVEIRA, MARCIA S.; SANTAMARIA, MAURO P.; COSTA, ANDRE LUIZ F.; LOPES, SERGIO. Texture analysis of cone-beam computed tomography images assists the detection of furcal lesion. Journal of Periodontology, v. 91, n. 9, . (18/17850-0, 17/09550-4)
MANSMITH CALLE, ALISON JHISEL; OGAWA, CELSO MASSAHIRO; MARTINS, JAQUELINE SERRA; SANTOS, FERNANDA CARDOSO; PEREIRA DE CASTRO LOPES, SERGIO LUCIO; RAPHAELLI NAHAS-SCOCATE, ANA CARLA; HASSEUS, BENGT; APPENZELLER, SIMONE; FERREIRA COSTA, ANDRE LUIZ. Temporomandibular joint in juvenile idiopathic arthritis: magnetic resonance imaging measurements and their correlation with imaging findings. Oral Radiology, . (17/09550-4, 19/22315-0)
FRANCO RICARDO, ANA LUCIA; DA SILVA, GABRIEL ARAUJO; OGAWA, CELSO MASSAHIRO; NUSSI, AMANDA D.; DE ROSA, CATHARINA SIMIONE; MARTINS, JAQUELINE SERRA; PEREIRA DE CASTRO LOPES, SERGIO LUCIO; APPENZELLER, SIMONE; BRAZ-SILVA, PAULO HENRIQUE; FERREIRA COSTA, ANDRE LUIZ. Magnetic resonance imaging texture analysis for quantitative evaluation of the mandibular condyle in juvenile idiopathic arthritis. Oral Radiology, v. N/A, p. 12-pg., . (17/09550-4, 19/00495-6, 20/08883-2)

Please report errors in scientific publications list using this form.
X

Report errors in this page


Error details: