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New conductive devices for application in electrochemical sensing and biosensing

Grant number: 17/21898-6
Support Opportunities:Regular Research Grants
Duration: February 01, 2018 - January 31, 2020
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal Investigator:Bruno Campos Janegitz
Grantee:Bruno Campos Janegitz
Host Institution: Centro de Ciências Agrárias (CCA). Universidade Federal de São Carlos (UFSCAR). Araras , SP, Brazil

Abstract

The electrochemical sensors and biosensors can facilitate the resolution of modern problems relatively quickly. The need for new methodologies and improvements in disease detection processes, aiming for accuracy and speed, leads to the development of new technologies. Therefore, analysis of diseases that would take weeks can be carried out in a few hours, with high accuracy and reliability. Based on screen-printing and electrochemical techniques, we aim to develop disposable electrodes with relative low cost by using environmentally friendly materials. In this context, the objective of this project is a proposal of new electrochemical sensors and biosensors, by using disposables, versatiles and low cost platforms such as PET and paper. In a first step, it will prepared conductive inks with polym,ers and carbon materials. In a second moment, electrodes will be prepared from the electro-spinning technique. As a form of application, we propose the use of these disposable electrodes in the electrochemical detection of biomarkers related to Alzheimer's and Parkinson's diseases. It is expected to obtain devices with high sensitivity, wide linear ranges, stable, with low detection limits and robust. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Scientific publications (18)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
RAYMUNDO-PEREIRA, PAULO A.; SILVA, TIAGO A.; CAETANO, FABIO R.; RIBOVSKI, LAIS; ZAPP, EDUARDO; BRONDANI, DANIELA; BERGAMINI, MARCIO F.; MARCOLINO, JR., LUIZ H.; BANKS, CRAIG E.; OLIVEIRA, JR., OSVALDO N.; et al. Polyphenol oxidase-based electrochemical biosensors: A review. Analytica Chimica Acta, v. 1139, p. 198-221, . (16/01919-6, 18/22214-6, 17/21097-3, 17/21898-6, 20/01050-5)
VIDAL RAMOS, MATHEUS MESQUITA; CARVALHO, JEFFERSON H. S.; DE OLIVEIRA, PAULO ROBERTO; JANEGITZ, BRUNO CAMPOS. Determination of serotonin by using a thin film containing graphite, nanodiamonds and gold nanoparticles anchored in casein. MEASUREMENT, v. 149, . (17/21898-6, 19/01844-4, 17/21097-3)
DOS SANTOS, FABRICIO A.; VIEIRA, NIRTON C. S.; ZAMBIANCO, NAIARA A.; JANEGITZ, BRUNO C.; ZUCOLOTTO, VALTENCIR. The layer-by-layer assembly of reduced graphene oxide films and their application as solution-gated field-effect transistors. Applied Surface Science, v. 543, . (17/21898-6, 18/07508-3, 17/21097-3)
DE ARAUJO ANDREOTTI, ISABELA APARECIDA; ORZARI, LUIZ OTAVIO; CAMARGO, JESSICA ROCHA; FARIA, RONALDO CENSI; MARCOLINO-JUNIOR, LUIZ HUMBERTO; BERGARNINI, MARCIO FERNANDO; GATTI, ALEXANDRE; JANEGITZ, BRUNO C.. Disposable and flexible electrochemical sensor made by recyclable material and low cost conductive ink. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 840, p. 109-116, . (17/21898-6, 16/12697-4, 18/02162-1)
ORZARI, LUIZ OTAVIO; DE FREITAS, RAFAELA CRISTINA; DE ARAUJO ANDREOTTI, ISABELA APARECIDA; GATTI, ALEXANDRE; JANEGITZ, BRUNO CAMPOS. A novel disposable self-adhesive inked paper device for electrochemical sensing of dopamine and serotonin neurotransmitters and biosensing of glucose. BIOSENSORS & BIOELECTRONICS, v. 138, . (17/21898-6, 16/12697-4)
ZAMBIANCO, NAIARA ALANA; SILVA, TIAGO ALMEIDA; ZANIN, HUDSON; FATIBELLO-FILHO, ORLANDO; JANEGITZ, BRUNO CAMPOS. Novel electrochemical sensor based on nanodiamonds and manioc starch for detection of diquat in environmental samples. DIAMOND AND RELATED MATERIALS, v. 98, . (17/21898-6, 17/11958-1, 17/21097-3, 14/02163-7)
DE OLIVEIRA, GABRIELA CAROLINA MAURUTO; CAMARGO, JESSICA ROCHA; VIEIRA, NIRTON CRISTI SILVA; JANEGITZ, BRUNO CAMPOS. A new disposable electrochemical sensor on medical adhesive tape. Journal of Solid State Electrochemistry, v. 24, n. 10, . (17/21898-6, 17/21097-3, 17/17572-8, 19/23177-0)
OLIANI PEDRO DA SILVA, VINICIUS APARECIDO; DE FREITAS, RAFAELA CRISTINA; DE OLIVEIRA, PAULO ROBERTO; MOREIRA, ROGER CARDOSO; MARCOLINO-JUNIOR, LUIZ HUMBERTO; BERGAMINI, MARCIO FERNANDO; COLTRO, WENDELL K. T.; JANEGITZ, BRUNO CAMPOS. Microfluidic paper-based device integrated with smartphone for point-of-use colorimetric monitoring of water quality index. MEASUREMENT, v. 164, . (17/21898-6, 19/01844-4, 17/21097-3)
ITKES, MARINA P. M.; DE OLIVEIRA, GEISER G.; SILVA, TIAGO ALMEIDA; FATIBELLO-FILHO, ORLANDO; JANEGITZ, BRUNO C.. Voltammetric sensing of fenitrothion in natural water and orange juice samples using a single-walled carbon nanohorns and zein modified sensor. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 840, p. 21-26, . (17/21898-6, 17/24618-4, 11/13312-5)
JODAR, LETICIA VIEIRA; ORZARI, LUIZ OTAVIO; ORTOLANI, TULIO STORTI; ASSUMPCAO, MONICA H. M. T.; VICENTINI, FERNANDO C.; JANEGITZ, BRUNO C.. Electrochemical Sensor Based on Casein and Carbon Black for Bisphenol A Detection. Electroanalysis, v. 31, n. 11, . (15/19099-2, 17/21898-6)
ORZARI, LUIZ O.; SANTOS, FABRICIO A.; JANEGITZ, BRUNO C.. Manioc starch thin film as support of reduced graphene oxide: A novel architecture for electrochemical sensors. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 823, p. 350-358, . (17/21898-6, 15/19099-2, 16/12697-4)
RAYMUNDO-PEREIRA, PAULO A.; BACCARIN, MARINA; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO C.. Thin Films and Composites Based on Graphene for Electrochemical Detection of Biologically-relevant Molecules. Electroanalysis, v. 30, n. 9, p. 1888-1896, . (16/01919-6, 17/21898-6, 13/14262-7)
MAURUTO DE OLIVEIRA, GABRIELA C.; DE SOUZA CARVALHO, JEFFERSON HENRIQUE; BRAZACA, LAIS CANNIATTI; SILVA VIEIRA, NIRTON CRISTI; JANEGITZ, BRUNO CAMPOS. Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers. BIOSENSORS & BIOELECTRONICS, v. 152, . (17/17572-8, 18/07508-3, 19/04085-7, 17/21097-3, 18/19750-3, 17/21898-6)
KALINKE, CRISTIANE; NEUMSTEIR, NAILE VACILOTTO; APARECIDO, GABRIEL DE OLIVEIRA; DE BARROS FERRAZ, THIAGO VASCONCELOS; DOS SANTOS, PAMYLA LAYENE; JANEGITZ, BRUNO CAMPOS; BONACIN, JULIANO ALVES. Comparison of activation processes for 3D printed PLA-graphene electrodes: electrochemical properties and application for sensing of dopamine. ANALYST, v. 145, n. 4, p. 1207-1218, . (17/23960-0, 17/21898-6, 17/21097-3, 19/00473-2, 13/22127-2)
BRAZACA, LAIS CANNIATTI; SAMPAIO, ISABELLA; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO CAMPOS. Applications of biosensors in Alzheimer's disease diagnosis. Talanta, v. 210, . (17/21898-6, 17/21097-3, 15/02623-0, 18/19750-3)
ORTOLANI, TULIO S.; PEREIRA, TAMIRES S.; ASSUMPCAO, MONICA H. M. T.; VICENTINI, FERNANDO C.; DE OLIVEIRA, GEISER GABRIEL; JANEGITZ, BRUNO C.. Electrochemical sensing of purines guanine and adenine using single-walled carbon nanohorns and nanocellulose. Electrochimica Acta, v. 298, p. 893-900, . (17/21898-6)
PRADEL-FILHO, LAURO A.; ANDREOTTI, ISABELA A. A.; CARVALHO, JEFFERSON H. S.; ARAUJO, DIELE A. G.; ORZARI, LUIZ O.; GATTI, ALEXANDRE; TAKEUCHI, REGINA M.; SANTOS, ANDRE L.; JANEGITZ, BRUNO C.. Glass varnish-based carbon conductive ink: A new way to produce disposable electrochemical sensors. SENSORS AND ACTUATORS B-CHEMICAL, v. 305, . (16/12697-4, 17/21898-6, 17/21097-3, 19/04085-7)
CAMARGO, JESSICA R.; ANDREOTTI, ISABELLA A. A.; KALINKE, CRISTIANE; HENRIQUE, JULIA M.; BONACIN, JULIANO A.; JANEGITZ, BRUNO C.. Waterproof paper as a new substrate to construct a disposable sensor for the, electrochemical determination of paracetamol and melatonin. Talanta, v. 208, . (17/21898-6, 18/02162-1, 17/21097-3, 19/00473-2, 13/22127-2)

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Filed patent(s) as a result of this research project

ELETRODOS FLEXÍVEIS DE PLATINA UTILIZADOS COMO BIOSSENSORES ELETROQUÍMICOS PARA DETERMINAÇÃO DE BIOMARCADORES RELACIONADOS AO MAL DE PARKINSON E MÉTODO DE FABRICAÇÃO BR1020200109790 - Universidade Federal de São Carlos (UFSCAR) . BRUNO CAMPOS JANEGITZ / GABRIELA CAROLINA MAURUTO DE OLIVEIRA / JEFFERSON HENRIQUE DE SOUZA CARVALHO / LAÍS CANNIATTI BRAZACA / NIRTON CRISTI SILVA VIEIRA - May 2020, 29