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INCT 2014: National Institute of Science and Technology in Bioanalysis

Grant number: 14/50867-3
Support Opportunities:Research Projects - Thematic Grants
Duration: July 01, 2017 - June 30, 2025
Field of knowledge:Physical Sciences and Mathematics - Chemistry
Convênio/Acordo: CNPq - INCTs
Principal Investigator:Lauro Tatsuo Kubota
Grantee:Lauro Tatsuo Kubota
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Pesquisadores principais:
( Atuais )
Auro Atsushi Tanaka ; Emanuel Carrilho ; Érico Marlon de Moraes Flores ; Lucio Angnes ; Marília Oliveira Fonsec Goulart ; Ronei Jesus Poppi ; Wendel Andrade Alves
Pesquisadores principais:
( Anteriores )
Marco Aurelio Zezzi Arruda
Associated grant(s):17/26037-9 - Multi-user equipment approved in grant 14/50867-3: Scanning Electrochemical Microscopy and optical surface profiler, AP.EMU
Associated scholarship(s):23/01723-8 - 3D printed electrochemical biosensors modified with nanostructured metal oxides generated from CO2 laser ablation, BP.PD
23/11363-9 - Manufacturing and development of microfluidic devices for point of care analysis applications, BP.TT
23/13068-4 - Peptide-based electrochemical biosensors for use in testing for anti-SARs-CoV-2, BP.PD
+ associated scholarships 23/10028-1 - Preparation of sustainable ink of carbon nanomaterials for applications to electrochemical sensors., BP.MS
23/01712-6 - Metabolomics of brain chemistry using LC-MS, BE.PQ
23/07602-8 - Nanomethalomics applied to soybean corns, BP.TT
23/09451-7 - Development of CRISPR-based biosensors for detection of disease-related genes, BP.PD
22/07571-2 - Development of a method for metabolomic analysis of exhaled air by GC×GC-MS with non-invasive collection based on sorption devices, BP.IC
21/08387-8 - Construction of an ultrasensitive biosensor for CRISPR-Cas12-based diagnosis for SARS-CoV-2 and variants detection without nucleic acid amplification, BP.PD
21/09706-0 - Development of a CRISPR/Cas-based electrochemical biosensor for T-Cell Leukemia virus (HTLV-1) and Staphylococcus Aureus bacteria detection with point-of-care devices, BP.DR
20/07195-5 - Development of analytical device for newborn screening using dried matrix spot and paper spray mass spectrometry, BP.PD
19/19235-4 - Dispersive magnetic solid-phase microextraction employing microfluidic platform: application to multiplexed determinations of antibiotics, aflatoxins and the diagnosis Mastitis in milk, BP.PD
19/12556-0 - Strategies for food authentication using multidimensional chromatography combined with microextraction microtechniques, BP.IC
19/00166-2 - Paper-Based Electrochemical Biosensor for Traumatic Brain Injury detection, BP.PD
18/19750-3 - Exploring C4D detection for the development of innovative and low-cost microfluidic biosensors, BP.PD
18/13496-8 - CHARACTERIZATION OF SYNTHETIC DRUGS AS ADULTERANTS IN DIETARY SUPPLEMENTS: USE OF VOLTAMMETRY OF IMMOBILIZED MICROPARTICLES IN SOLID STATE AS ANALYTICAL METHODOLOGY, BP.PD
18/03956-1 - Development and application of the novelty SPME device - Coated Blade Spray, BP.PD
16/20547-2 - Characterization of the metabolome of anti-phytopatogen microorganisms by Multidimensional Gas Chromatography and Simple / Tandem Mass Spectrometry (GC×GC-QMS and GC×GC-MS/MS), BP.DR - associated scholarships

Abstract

Analytical Chemistry, in the last years, has directed great efforts to the development of analytical methods for the analysis of samples and/or analytes of biological interest. The huge impact of the researches in this area provided a race towards the development of methods for the chemical analyses of substances of live organisms. With the engagement of analytical chemists in the development of methods for biological, biochemical and clinical purposes, not only a very big increase in the works in this area was verified, but also the emergence of research groups working specifically in the area of analyses of biological samples. The importance of these works led to the birth of the area of bioanalytics, being a great focus of actuation of analytical chemists. In the country, however, bioanalytics is very incipient and some researchers work with different analytical techniques to develop methods of bioanalysis, despite the fact that this area is of great strategic importance to the country. Even in front of this strategic importance, little has been done so as to develop analytical tools for the diagnosis of diseases, disorders, pharmacological action, among others. In was in this context that the National Institute of Science and Technology of Bioanalytics - INCTBio was created in 2009, with the goal of carrying out coordinated works with exchange of information between the researchers in different areas of actuation so as to seek for the consolidation of the area in the country. Among the concerns in the creation of the institute of bioanalytics, there was the formation of human resources and the diffusion of the area in society, as well as the transfer to society of the benefits provided by the development of analytical tools for the improvement of life quality, be it in the speciation of biological molecules of interest, in the development of analytical methods that can provide fast and mostly real-time results, or in the use of mathematical tools when it is necessary to interpret complex data, among others described in the detailing of the lines of research inserted in this proposal. During the last 05 years of existence of the INCTBio, the group counted with the partnership and collaboration of 39 researchers from 22 different institutions. Initially, we sought to select the best researchers to be part of the group, taking into consideration the regional issue, institutions and young researchers. One of the goals of the group was the consolidation and strengthening of young researchers and recent institutions without great tradition in research. Today, these groups have been consolidated and many of them have become reference in bioanalytics in the country, impelling the development of science in regions that were forgotten in the scientific scenario. The development of projects inside the INCTBio adjusted to the emergent necessities, focused on the strategic interest of the country, as it was emphasized by the advisor of the fourth report: “Faced by the fact that the group of the project includes the majority of the exponents of the Instrumental Analytical Chemistry of the country, both in the employment of techniques and equipment of latest generation, and in the development of devices and patentable methods for clinical analyses of national interest, the fact that the fourth report proves important advances in the original project and points to new researches in the more biological area (metabolomics) and discoveries resulting from the work already realized and published, does not surprise”. The scientific production of the Institute in these 05 years was extremely intense, being “admirable” in the advisor’s words. In total, 563 articles were published (without considering the articles of 2014-2015), and of these, 66 were in national journals and 497 in international ones. It is worth emphasizing that the number of published articles followed an ascendant, year to year, presenting an increase superior to 400%, going from 46 articles in 2009 to 200 articles in 2013, having an average impact factor of 3.1 of all the publications. The formation of human resources was one of the main points of interest of the Institute, permitting bioanalytics to become a solid and strong area in the country, guaranteeing the continuity of the scientific development in this strategic area, and once more, citing the advisor of the fourth report: “Without doubt, the scientific production of the group of researchers of the INCTBio is admirable. In this report, the publication of 259 articles in journals of medium and high impact in the areas of Analytical Chemistry, Materials and Biotechnology, the requirement of 05 patents, nearly 200 participations in national and international congresses, 09 book chapters and 12 awards are pointed. 04 projects were established together with companies and the covenant with the INC-DF”. Apart from the productions already mentioned, the INCTBio contributed with 10 book chapters, 08 patents and products were required and 02 were licensed, and it received 12 awards. In the period from 2009 to 2013, the INCTBio formed 110 specialists in the area of bioanalytics, being 67 masters and 43 doctors, and apart from these, it counted with the collaboration of approximately 50 post-doctoral students and contributed to the academic formation of 112 Scientific Initiation students, attracting more and more graduate students to this theme. (AU)

Articles published in Agência FAPESP Newsletter about the research grant:
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Scientific publications (305)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
FREITAS, DANIEL C.; DE ANDRADE, ALINE M.; DA COSTA, LUANA F.; AZEVEDO, RICARDO A.; ARRUDA, MARCO A. Z.. There is plenty of room at the plant science: A review of nanoparticles applied to plant cultures. Annals of Applied Biology, v. 178, n. 2, SI, p. 149-168, . (20/02020-2, 14/50867-3, 18/25207-0)
GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, . (13/24725-4, 18/21489-1, 18/16896-7, 14/50867-3, 17/13137-5)
DE SOUZA PESSOA, GUSTAVO; DE JESUS, JEMMYSON ROMARIO; BALBUENA, TIAGO SANTANA; ARRUDA, MARCO AURELIO ZEZZI. Metallomics-based platforms for comparing the human blood serum profiles between bipolar disorder and schizophrenia patients. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, . (14/50867-3, 18/25207-0, 16/07384-7)
HRYNIEWICZ, BRUNA M.; WOLFART, FRANCIELE; GOMEZ-ROMERO, PEDRO; ORTH, ELISA S.; VIDOTTI, MARCIO. Enhancement of organophosphate degradation by electroactive pyrrole and imidazole copolymers. Electrochimica Acta, v. 338, . (14/50867-3)
MA, HUI LING; VARANDA, LAUDEMIR CARLOS; PERUSSI, JANICE RODRIGUES; CARRILHO, EMANUEL. Hypericin-loaded oil-in-water nanoemulsion synthesized by ultrasonication process enhances photodynamic therapy efficiency. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, v. 223, . (13/01284-2, 13/07276-1, 14/50867-3)
CRUCELLO, JULIANA; MEDEIROS JUNIOR, IRIS; DE CARVALHO, ROGERIO MESQUITA; HANTAO, LEANDRO WANG. Profiling organic acids in produced water samples using vacuum-assisted sorbent extraction and gas chromatography coupled to Fourier transform Orbitrap mass spectrometry. Microchemical Journal, v. 180, p. 8-pg., . (20/01064-6, 14/50867-3, 19/11353-8)
EFFTING, LUCIANE; PRETE, MAIYARA CAROLYNE; URBANO, ALEXANDRE; EFFTING, LETICIA MARIA; CANO GONZALEZ, MARIO EDUARDO; BAIL, ALESANDRO; TEIXEIRA TARLEY, CESAR RICARDO. Preparation of magnetic nanoparticle-cholesterol imprinted polymer using semi-covalent imprinting approach for ultra-effective and highly selective cholesterol adsorption. REACTIVE & FUNCTIONAL POLYMERS, v. 172, p. 12-pg., . (14/50867-3)
MOREAU, PEDRO DOS SANTOS; ZEZZI ARRUDA, MARCO AURELIO. Direct analysis of tree rings using laser ablation-ICP-MS and quantitative evaluation of Zn and Cu using filter paper as a solid support for calibration. Journal of Analytical Atomic Spectrometry, v. 37, n. 4, p. 10-pg., . (19/00018-3, 18/25207-0, 14/50867-3, 17/50085-3, 19/24445-8)
RIBEIRO, LIGIA N. M.; FRANZ-MONTAN, MICHELLE; ALCANTARA, ANA C. S.; BREITKREITZ, MARCIA C.; CASTRO, SIMONE R.; GUILHERME, VIVIANE A.; MUNIZ, V, BRUNO; RODRIGUES DA SILVA, GUSTAVO H.; DE PAULA, ENEIDA. Hybrid nanofilms as topical anesthetics for pain-free procedures in dentistry. SCIENTIFIC REPORTS, v. 10, n. 1, . (14/50867-3, 14/25372-0, 14/14457-5)
BARRETO, TULIO ROLIM; GORLA, FELIPE AUGUSTO; FERREIRA, MILENA DO PRADO; ARAUJO DUARTE, PEDRO HENRIQUE; RIBEIRO, EMERSON SCHWINGEL; AFONSO, JULIO CARLOS; TEIXEIRA TARLEY, CESAR RICARDO. Synthesis and Characterization of a Silica/Tungsten(VI) Oxide and Its Performance for the On-Line Solid-Phase Extraction (SPE) of Nickel Ions from Aqueous Media with Determination by Flame Atomic Absorption Spectrometry (FAAS). Analytical Letters, v. 54, n. 7, . (14/50867-3)
GONCALVES, JOSUE M.; MATIAS, TIAGO A.; ANGNES, LUCIO; MARTINS, PAULO R.; ARAKI, KOITI. Review-Tetraruthenated Porphyrins and Composites as Catalysts and Sensor Materials: A Short Review. ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY, v. 9, n. 6, . (13/24725-4, 18/16896-7, 17/13137-5, 18/21489-1, 17/50129-0, 14/50867-3)
PASCHOALINO, WALDEMIR J.; PAYNE, NICHOLAS A.; PESSANHA, TATIANA M.; GATEMAN, SAMANTHA M.; KUBOTA, LAURO T.; MAUZEROLL, JANINE. Charge Storage in Graphene Oxide: Impact of the Cation on Ion Permeability and Interfacial Capacitance. Analytical Chemistry, v. 92, n. 15, p. 10300-10307, . (14/50867-3, 18/12910-5, 17/05213-3, 13/22127-2)
BARROS AZEREDO, NATHALIA FLORENCIA; FERREIRA SANTOS, MAURO S.; SEMPIONATTO, JULIANE R.; WANG, JOSEPH; ANGNES, LUCIO. Screen-Printed Technologies Combined with Flow Analysis Techniques: Moving from Benchtop to Everywhere. Analytical Chemistry, v. 94, n. 1, p. 19-pg., . (14/50867-3)
SOUZA, RITA C. Z.; ZANDONADI, FLAVIA S.; FREITAS, DONIZETE P.; TOFOLI, LUIS F. F.; SUSSULINI, ALESSANDRA. Validation of an analytical method for the determination of the main ayahuasca active compounds and application to real ayahuasca samples from Brazil. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, v. 1124, p. 197-203, . (14/50867-3, 18/01525-3)
COSTA, BRENDA M. C.; PRADO, ALICEANA A.; OLIVEIRA, THIAGO C.; BRESSAN, LUCAS P.; MUNOZ, RODRIGO A. A.; BATISTA, ALEX D.; DA SILVA, JOSE A. F.; RICHTER, EDUARDO M.. Fast methods for simultaneous determination of arginine, ascorbic acid and aspartic acid by capillary electrophoresis. Talanta, v. 204, p. 353-358, . (14/50867-3)
CAJAMARCA SUQUILA, FABIO ANTONIO; SCHEEL, GUILHERME LUIZ; DE OLIVEIRA, FERNANDA MIDORI; TEIXEIRA TARLEY, CESAR RICARDO. Assessment of ultrasound-assisted extraction combined with supramolecular solvent-based microextraction for highly sensitive cadmium determination in medicinal plant sample by TS-FF-AAS. Microchemical Journal, v. 145, p. 1071-1077, . (14/50867-3)
KUDO, MARIANNE V. F.; DE OLIVEIRA, LEANDRO L. G.; SUQUILA, FABIO A. C.; DE ALMEIDA, FERNANDA G.; SEGATELLI, MARIANA G.; LIMA, EDER C.; DIAS, SILVIO L. P.; TARLEY, CESAR R. T.. Performance of Avocado Seed Activated Carbon as Adsorbent for Highly Sensitive Determination of Cd Using a Flow Injection System Online Coupled to TS-FF-AAS. Journal of the Brazilian Chemical Society, v. 31, n. 1, p. 100-108, . (14/50867-3)
BRESSAN, LUCAS P.; ADAMO, CRISTINA B.; QUERO, REVERSON F.; DE JESUS, DOSIL P.; DA SILVA, JOSE A. F.. A simple procedure to produce FDM-based 3D-printed microfluidic devices with an integrated PMMA optical window. ANALYTICAL METHODS, v. 11, n. 8, p. 1014-1020, . (14/50867-3, 18/06478-3)
SOUZA DE JESUS, FRANCIELLY FERNANDA; COELHO, MINE GUADALUPE; PALLOS, LAIS DE ASSIS; FRACASSI DA SILVA, JOSE ALBERTO; DANIEL, DANIELA; DE JESUS, DOSIL PEREIRA. Simple and fast method for simultaneous determination of propionate and sorbate in bread by capillary electrophoresis with UV spectrophotometric detection. Journal of Food Composition and Analysis, v. 72, p. 93-96, . (14/50867-3, 13/22127-2)
HRYNIEWICZ, BRUNA M.; WINNISCHOFER, HERBERT; VIDOTTI, MARCIO. Interfacial characterization and supercapacitive behavior of PEDOT nanotubes modified electrodes. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 823, p. 573-579, . (14/50867-3)
HRYNIEWICZ, BRUNA M.; BACH-TOLEDO, LARISSA; VIDOTTI, MARCIO. Harnessing energy from micropollutants electrocatalysis in a high-performance supercapacitor based on PEDOT nanotubes. APPLIED MATERIALS TODAY, v. 18, . (14/50867-3)
MELLO, LUCAS R.; HAMLEY, IAN W.; CASTELLETTO, VALERIA; GARCIA, BIANCA B. M.; LOURENCO, THIAGO C.; VASSILIADES, SANDRA V.; ALVES, WENDEL A.; HAN, SANG W.; SILVA, EMERSON R.. Self-assembly and intracellular delivery of DNA by a truncated fragment derived from the Trojan peptide Penetratin. SOFT MATTER, v. 16, n. 20, p. 4746-4755, . (14/50867-3, 17/02317-2, 16/24409-3, 15/24018-1)
ROSSINI, PAMELA DE O.; LAZA, ANABEL; AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; FELIX, FABIANA S.; ARAKI, KOITI; ANGNES, LUCIO. Ni-based double hydroxides as electrocatalysts in chemical sensors: A review. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 126, . (18/21489-1, 14/50867-3, 17/13137-5, 18/16896-7)
DE OLIVEIRA NEVES, LEANDRA NATALIA; LEAL DE OLIVEIRA, MARCONE AUGUSTO. Effects of enzymatic lactose hydrolysis on thermal markers in lactose-free UHT milk. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, v. 57, n. 9, . (14/50867-3)
CAPELARI, TAINARA BOARETO; PEREIRA, ARNALDO CESAR; GONCALVES DE OLIVEIRA, LEANDRO LUAN; TEIXEIRA TARLEY, CESAR RICARDO. Sensitive Simultaneous Determination of o-Nitrophenol and p-Nitrophenol in Water by Surfactant-Mediated Differential Pulse Voltammetry. Analytical Letters, v. 52, n. 9, p. 1462-1476, . (14/50867-3)
MONTE, GABRIELA GUILHERME; NANI, V, JOAO; DE ALMEIDA CAMPOS, MARINA ROSSETO; DAL MAS, CAROLINE; NEGRI MARINS, LUCAS AUGUSTO; MARTINS, LUCAS GELAIN; TASIC, LJUBICA; MORI, MARCELO A.; HAYASHI, MIRIAN A. F.. Impact of nuclear distribution element genes in the typical and atypical antipsychotics effects on nematode Caenorhabditis elegans: Putative animal model for studying the pathways correlated to schizophrenia. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 92, p. 19-30, . (14/50867-3, 15/07019-4, 13/13392-4, 17/02413-1, 18/06510-4)
PRETE, MAIYARA C.; DOS SANTOS, DAYANA M.; EFFTING, LUCIANE; TARLEY, CESAR R. T.. Preparation of Molecularly Imprinted Poly(methacrylic acid) Grafted on Iniferter-Modified Multiwalled Carbon Nanotubes by Living-Radical Polymerization for 17 beta-Estradiol Extraction. JOURNAL OF CHEMICAL AND ENGINEERING DATA, v. 64, n. 5, SI, p. 1978-1990, . (14/50867-3)
FERREIRA, MILENA DO PRADO; TARLEY, CESAR RICARDO TEIXEIRA. ioaccessibility estimation of metallic macro and micronutrients Ca, Mg, Zn, Fe, Cu and Mn in flours of oat and passion fruit pee. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 150, . (14/50867-3)
DE OLIVEIRA NEVES, LEANDRA N.; LEAL DE OLIVEIRA, MARCONE A.. Assessment of enzymatic hydrolysis of lactose in lactose-free milk production - A comparative study using capillary zone electrophoresis and cryoscopy. LWT-FOOD SCIENCE AND TECHNOLOGY, v. 138, . (14/50867-3)
GONCALVES, JOSUE M.; IGLESIAS, BERNARDO A.; MARTINS, PAULO R.; ANGNES, LUCIO. Recent advances in electroanalytical drug detection by porphyrin/phthalocyanine macrocycles: developments and future perspectives. ANALYST, v. 146, n. 2, p. 365-381, . (18/16896-7, 17/13137-5, 14/50867-3)
TEIXEIRA TARLEY, CESAR RICARDO; CAJAMARCA SUQUILA, FABIO ANTONIO; CASARIN, JULIANA; GONCALVES JUNIOR, AFFONSO CELSO; SEGATELLI, MARIANA GAVA. Development of selective preconcentration/clean-up method for imidazolinone herbicides determination in natural water and rice samples by HPLC-PAD using an imazethapyr imprinted poly(vinylimidazole-TRIM). Food Chemistry, v. 334, . (14/50867-3)
GONCALVES, JOSUE M.; DA SILVA, MATHEUS I.; HASHEMINEJAD, MEISAM; TOMA, HENRIQUE E.; ARAKI, KOITI; MARTINS, PAULO R.; ANGNES, LUCIO. Recent Progress in Core@Shell Sulfide Electrode Materials for Advanced Supercapacitor Devices. BATTERIES & SUPERCAPS, v. 4, n. 9, p. 1397-1427, . (18/21489-1, 18/16896-7, 14/50867-3, 13/24725-4, 17/13137-5)
PELISSARI, MARCELO RODRIGUES DA SILVA; AZEVEDO NETO, NILTON FRANCELOSI; CAMARGO, LUAN PEREIRA; DALL'ANTONIA, LUIZ HENRIQUE. Characterization and Photo-Induced Electrocatalytic Evaluation for BiVO4 Films Obtained by the SILAR Process. ELECTROCATALYSIS, v. 12, n. 3, . (14/50867-3)
SATO, RENATA TAKABAYASHI; ALVES, JULIA BRUCE; AMORIM, TATIANE LIMA; LEAL DE OLIVEIRA, MARCONE AUGUSTO. A capillary electrophoresis method for free fatty acids screening and acidity determination in biodiesel. ELECTROPHORESIS, v. 42, n. 9-10, . (14/50867-3)
POLLO, BRENO JORGE; TEIXEIRA, CARLOS ALBERTO; BELINATO, JOAO RAUL; FURLAN, MAYRA FONTES; DE MATOS CUNHA, ISABELA CRISTINA; VAZ, CAROLINE ROCHA; VOLPATO, GUSTAVO VERONEZI; AUGUSTO, FABIO. Chemometrics, Comprehensive Two-Dimensional gas chromatography and ``omics{''} sciences: Basic tools and recent applications. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 134, . (19/12556-0, 14/50867-3, 18/25729-7)
AZEREDO, NATHALIA F. B.; GONCALVES, JOSUE M.; ROSSINI, PAMELA O.; ARAKI, KOITI; WANG, JOSEPH; ANGNES, LUCIO. Uric acid electrochemical sensing in biofluids based on Ni/Zn hydroxide nanocatalyst. Microchimica Acta, v. 187, n. 7, . (14/50867-3, 17/13137-5, 18/21489-1, 18/16896-7)
DA COSTA, PAULO VINICIUS F.; DA SILVA, REJANE MARIA P.; SUFFREDINI, HUGO B.; ALVES, WENDEL A.. Poly-L-Arginine-Modified Boron-Doped Diamond and Glassy Carbon Electrodes for Terbutaline Sulfate Detection. Journal of Nanoscience and Nanotechnology, v. 18, n. 7, p. 4551-4558, . (15/24018-1, 14/50867-3)
ROCHA, BRUNO ALVES; DE OLIVEIRA, SILVANA RUELLA; DA SILVA, RODRIGO MOREIRA; MAZZARON BARCELOS, GUSTAVO RAFAEL; MORAES DE OLIVEIRA, ANDERSON RODRIGO; BARBOSA JR, FERNANDO. An eco-friendly sample preparation procedure base on low-density solvent-based air-assisted liquid-liquid microextraction for the simultaneous determination of 21 potential endocrine disruptors in urine samples by liquid chromatography-tandem mass spectrometry. Microchemical Journal, v. 147, p. 207-214, . (14/50945-4, 14/50867-3, 18/07534-4, 14/19914-5)
MA, HUI LING; URBACZEK, ANA CAROLINA; RIBEIRO DE SOUZA, FAYENE ZEFERINO; GOMES GARRIDO CARNEIRO LEAO, PAULO AUGUSTO; PERUSSI, JANICE RODRIGUES; CARRILHO, EMANUEL. Rapid Fabrication of Microfluidic Devices for Biological Mimicking: A Survey of Materials and Biocompatibility. MICROMACHINES, v. 12, n. 3, . (14/50867-3, 15/17145-7)
CASTIBLANCO, EDUARDO BALLEN; QUERO, REVERSON FERNANDES; DE OLIVEIRA, AMILTON MOREIRA; DE JESUS, DOSIL PEREIRA; HANTAO, LEANDRO WANG. Improving selective channel occlusion of complex hydrocarbons and fatty acid methyl esters in urea crystals by using an expendable 3D-printed microfluidic device for sample preparation in untargeted petroleomics. Analytica Chimica Acta, v. 1160, . (20/01064-6, 13/22127-2, 14/50867-3, 17/00358-3)
ARRUDA, MARCO AURELIO ZEZZI; JESUS, JEMMYSON ROMARIO DE; BLINDAUER, CLAUDIA ANDREA; STEWART, ALAN JAMES. Speciomics as a concept involving chemical speciation and omics. JOURNAL OF PROTEOMICS, v. 263, p. 8-pg., . (20/08543-7, 19/00018-3, 18/25207-0, 14/50867-3, 17/50085-3, 19/24445-8)
ULLOA ROJAS, JOSE EDUARDO; DE OLIVEIRA, VIVIAN LEITE; DE ARAUJO, DANIELE RIBEIRO; TOFOLI, GIOVANA RADOMILLE; DE OLIVEIRA, MATHEUS MENDES; CARASTAN, DANILO JUSTINO; PALACI, MOISES; GIUNTINI, FRANCESCA; ALVES, WENDEL ANDRADE. Silk Fibroin/Poly(vinyl Alcohol) Microneedles as Carriers for the Delivery of Singlet Oxygen Photosensitizers. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 8, n. 1, p. 12-pg., . (14/50867-3)
MOREIRA DE OLIVEIRA, AMILTON; TEIXEIRA, CARLOS ALBERTO; HANTAO, LEANDRO WANG. Advanced tuning of the ion management parameters in GC x GC-HRMS using a Fourier transform Orbitrap mass analyzer for pixel-based data handling and multivariate analysis. ANALYTICAL METHODS, v. 14, n. 16, p. 9-pg., . (19/11353-8, 20/01064-6, 14/50867-3)
LORENZEN, ANA LUIZA; SILYA, RAFAEL J.; KLOBUKOSKI, VANESSA; SOARES, FREDERICO L. F.; FORNARI, MAYARA R.; MANGRICH, ANTONIO S.; VIDOTTI, MARCIO. Ultrasonic-Assisted Synthesis of Nanosized Graphite Obtained from Biomass and Its Assembly in Polyaniline-Composite Material for Energy Storage. ENERGY & FUELS, v. N/A, p. 10-pg., . (14/50867-3)
DA SILVA PELISSARI, MARCELO RODRIGUES; CAMARGO, LUAN PEREIRA; CATARINI DA SILVA, PAULO ROGERIO; DALL'ANTONIA, LUIZ HENRIQUE. Fe2V4O13 photoanode material: an interesting approach to non-enzymatic glucose oxidation. Journal of Materials Science, v. 57, n. 14, p. 18-pg., . (14/50867-3)
ANGELIS, PEDRO NUNES; MENDONCA, JHESSICA DE CASSIA; DA ROCHA, LUANA RIANNE; CAPELARI, TAINARA BOARETO; PRETE, MAIYARA CAROLYNE; SEGATELLI, MARIANA GAVA; BORSATO, DIONISIO; TARLEY, CESAR RICARDO TEIXEIRA. Feasibility of a Nano-Carbon Black Paste Electrode for Simultaneous Voltammetric Determination of Antioxidants in Food Samples and Biodiesel in the Presence of Surfactant. Electroanalysis, v. 32, n. 6, . (14/50867-3)
KAASIK, HELLE; SOUZA, RITA C. Z.; ZANDONADI, FLAVIA S.; TOFOLI, LUIS FERNANDO; SUSSULINI, ALESSANDRA. Chemical Composition of Traditional and Analog Ayahuasca. JOURNAL OF PSYCHOACTIVE DRUGS, v. 53, n. 1, . (14/50867-3, 18/01525-3)
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CARLA C. DECANDIO; SANDRA V. VASSILIADES; BARBARA B. GERBELLI; ANDREA M. AGUILAR; WENDEL A. ALVES. Hybrid Hydrogels Based on Polyethylene Glycol Bioconjugated with Silylated-Amyloidogenic Peptides. Journal of the Brazilian Chemical Society, v. 31, n. 11, p. 2200-2210, . (14/50867-3, 17/02317-2)
PAIVA, ANDRE CUNHA; CRUCELLO, JULIANA; PORTO, NATHALIA DE AGUIAR; HANTAO, LEANDRO WANG. Fundamentals of and recent advances in sorbent-based headspace extractions. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 139, . (14/50867-3, 19/11353-8, 20/01064-6)
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KOGIKOSKI, JR., SERGIO; PASCHOALINO, WALDEMIR J.; CANTELLI, LORY; SILVA, WILGNER; KUBOTA, LAURO T.. Electrochemical sensing based on DNA nanotechnology. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 118, p. 597-605, . (14/50867-3, 16/14507-8, 17/05213-3, 13/22127-2)
SOARES, ANA LETICIA; ZAMORA, MARTIN L.; MARCHESI, LUIS F.; VIDOTTI, MARCIO. Adsorption of catechol onto PEDOT films doped with gold nanoparticles: Electrochemical and spectroscopic studies. Electrochimica Acta, v. 322, . (14/50867-3)
FAVARO PEREZ, MARY ANGELA; PADULA, MARISA; MOITINHO, DAISY; GRESPAN BOTTOLI, CARLA BEATRIZ. Primary aromatic amines in kitchenware: Determination by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, v. 1602, p. 217-227, . (18/07234-0, 14/50867-3, 15/26300-6)
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KOGIKOSKI, JR., SERGIO; PASCHOALINO, WALDEMIR J.; KUBOTA, LAURO T.. Supramolecular DNA origami nanostructures for use in bioanalytical applications. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 108, p. 88-97, . (16/14507-8, 14/50867-3, 13/22127-2, 17/05213-3)
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LORENZEN, ANA L.; ROSSI, THAIS S.; RIEGEL-VIDOTTI, IZABEL C.; VIDOTTI, MARCIO. Influence of cationic and anionic micelles in the (sono)chemical synthesis of stable Ni(OH)(2) nanoparticles: ``In situ{''} zeta-potential measurements and electrochemical properties. Applied Surface Science, v. 455, p. 357-366, . (14/50867-3)
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PRETE, MAIYARA CAROLYNE; TEIXEIRA TARLEY, CESAR RICARDO. Bisphenol A adsorption in aqueous medium by investigating organic and inorganic components of hybrid polymer (polyvinylpyridine/SiO2/APTMS). CHEMICAL ENGINEERING JOURNAL, v. 367, p. 102-114, . (14/50867-3)
ROCHA, LUANA RIANNE; D'ELIA, ELIANE; MEDEIROS, ROBERTA ANTIGO; TEIXEIRA TARLEY, CESAR RICARDO. Electroanalytical Determination of Morpholine as a Corrosion Inhibitor at a Cathodically Pretreated Boron-Doped Diamond Electrode. Analytical Letters, v. 52, n. 7, p. 1083-1096, . (14/50867-3)
BRESSAN, LUCAS P.; ROBLES-NAJAR, JESSICA; ADAMO, CRISTINA B.; QUERO, REVERSON F.; COSTA, BRENDA M. C.; DE JESUS, DOSIL P.; DA SILVA, JOSE A. F.. 3D-printed microfluidic device for the synthesis of silver and gold nanoparticles. Microchemical Journal, v. 146, p. 1083-1089, . (14/50867-3, 14/50906-9, 18/06478-3)
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DE OLIVEIRA, AMILTON MOREIRA; TEIXEIRA, CARLOS ALBERTO; HANTAO, LEANDRO WANG. Evaluation of the retention profile in flow-modulated comprehensive two-dimensional gas chromatography and independent component analysis of weathered heavy oils. Microchemical Journal, v. 172, n. B, . (20/01064-6, 14/50867-3)
DA SILVA, ALEXSANDRA D.; PASCHOALINO, WALDEMIR J.; DAMASCENO, JOAO PAULO V.; KUBOTA, LAURO T.. Structure, Properties, and Electrochemical Sensing Applications of Graphene-Based Materials. CHEMELECTROCHEM, v. 7, n. 22, p. 4508-4525, . (17/05213-3, 14/50867-3, 13/22127-2)
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CAJAMARCA, FABIO ANTONIO; TEIXEIRA TARLEY, CESAR RICARDO. Influence of Synthesis Parameters and Polymerization Methods on the Selective and Adsorptive Performance of Bio-Inspired Ion Imprinted Polymers. SEPARATIONS, v. 9, n. 10, p. 27-pg., . (14/50867-3)
DA SILVA, ALEXSANDRA D.; PASCHOALINO, WALDEMIR J.; KUBOTA, LAURO T.. A Simple, sensitive, and selective electrochemical aptasensor for cortisol based on rGO-AuNPs. Electroanalysis, v. N/A, p. 12-pg., . (14/50867-3, 13/22127-2, 17/05213-3)
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DE OLIVEIRA NEVES, LEANDRA NATALIA; MARQUES, RAFAEL; FONSECA DA SILVA, PAULO HENRIQUE; LEAL DE OLIVEIRA, MARCONE AUGUSTO. Lactulose determination in UHT milk by CZE-UV with indirect detection. Food Chemistry, v. 258, p. 337-342, . (14/50867-3)
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DE OLIVEIRA, LEANDRO L. G.; SUQUILA, FABIO A. C.; DE OLIVEIRA, FERNANDA M.; SCHEEL, GUILHERME L.; TARLEY, CESAR R. T.. Synthesis and application of restricted access material-ion imprinted poly (allylthiourea) for selective separation of Cd2+ and humic acid exclusion. REACTIVE & FUNCTIONAL POLYMERS, v. 134, p. 93-103, . (14/50867-3)
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DUARTE, LUCAS MATTOS; AMORIM, TATIANE LIMA; GRAZUL, RICHARD MICHAEL; LEAL DE OLIVEIRA, MARCONE AUGUSTO. Differentiation of aromatic, bittering and dual-purpose commercial hops from their terpenic profiles: An approach involving batch extraction, GC-MS and multivariate analysis. Food Research International, v. 138, p. 8-pg., . (14/50867-3)
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WACHHOLZ JUNIOR, DAGWIN; DEROCO, PATRICIA BATISTA; KUBOTA, LAURO TATSUO. A copper-based metal-organic framework/reduced graphene oxide-modified electrode for electrochemical detection of paraquat. Microchimica Acta, v. 189, n. 8, p. 12-pg., . (21/09706-0, 19/00166-2, 13/22127-2, 14/50867-3)
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FREITAS, DANIEL C.; DE ANDRADE, ALINE M.; DA COSTA, LUANA F.; AZEVEDO, RICARDO A.; ARRUDA, MARCO A. Z.. There is plenty of room at the plant science: A review of nanoparticles applied to plant cultures. Annals of Applied Biology, v. 178, n. 2, p. 20-pg., . (20/02020-2, 14/50867-3, 18/25207-0)
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MARQUES, RAFAEL; LIMA, NERILSON M.; CANTARINO, LUIZ FELIPE; DE CARVALHO, GUSTAVO S. G.; LEITAO, ALEXANDRE A.; DO LAGO, CLAUDIMIR LUCIO; DE OLIVEIRA, MARCONE A. L.. [3-(Methacryloxy)propyl]trimethoxysilane-based monolithic stationary phases for capillary-scale chromatography and their characterization by contactless conductivity detection and solid-state NMR spectroscopy. Microchemical Journal, v. 161, . (14/50867-3)
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SHIROMA, LETICIA SAYURI; BOTTOLI, CARLA BEATRIZ GRESPAN; JONSSON, CLAUDIO MARTIN; QUEIROZ, SONIA C. N.. Exposure of tilapia (Oreochromis niloticus) to the antibiotic florfenicol in water: determination of the bioconcentration factor and the withdrawal period. Environmental Science and Pollution Research, v. 28, n. 29, p. 39026-39034, . (14/50867-3)
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DE OLIVEIRA NEVES, LEANDRA N.; LEAL DE OLIVEIRA, MARCONE A.. Quantification of lactose and lactulose in hydrolysed-lactose UHT milk using capillary zone electrophoresis. INTERNATIONAL DAIRY JOURNAL, v. 106, . (14/50867-3)
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KAWANO, DANIEL F.; COSTA, BRUNA Z.; ROMERO-OREJON, KATHERINE L.; LOUREIRO, HUGO C.; DE JESUS, DOSIL P.; MARSAIOLI, ANITA J.. The Enantiomeric Discrimination of 5-Hexyl-2-methyl-3,4-dihydro-2H-pyrrole by Sulfobutyl ether-beta-cyclodextrin: A Case Study. Molecules, v. 26, n. 9, p. 7-pg., . (14/50249-8, 18/08585-1, 13/22127-2, 14/50867-3)
BIANCHI, JAQUELINE; CAVICCHIOLI, RAFAEL; KUBOTA, LAURO T.; CARRILHO, EMANUEL; DE SOUSA, CRISTINA P.; FREITAS ANIBAL, FERNANDA DE. Antigenotoxic potential of the fermentation broth produced by Paenibacillus polymyxa RNC-D in vitro. FUTURE MICROBIOLOGY, v. 16, n. 7, p. 471-485, . (16/13423-5, 14/50867-3)
PIMENTEL VILLACA, CATHARINA DE BARROS; DE PAULA, CAROLINA CAVALCANTE; DE OLIVEIRA, CAROLINE CRUZ; VILAS-BOAS, ELOISA APARECIDA; DOS SANTOS-SILVA, JUNIA CAROLINA; DE OLIVEIRA, SERGIO FERREIRA; ABDULKADER, FERNANDO; FERREIRA, SANDRA MARA; ORTIS, FERNANDA. Beneficial effects of physical exercise for beta-cell maintenance in a type 1 diabetes mellitus animal model. Experimental Physiology, v. 106, n. 7, p. 1482-1497, . (14/50867-3, 17/04580-2, 19/26062-9)
DEROCO, PATRICIA BATISTA; WACHHOLZ JUNIOR, DAGWIN; KUBOTA, LAURO TATSUO. Recent advances in point-of-care biosensors for the diagnosis of neglected tropical diseases. SENSORS AND ACTUATORS B-CHEMICAL, v. 349, . (14/50867-3, 13/22127-2, 19/00166-2)
QUINTERO, MELISSA ESCOBAR; DE MORAES PONTES, JOAO GUILHERME; TASIC, LJUBICA. Metabolomics in degenerative brain diseases. Brain Research, v. 1773, . (14/50867-3, 18/24069-3)
LUPORINI, RAFAEL LUIS; POTT-JUNIOR, HENRIQUE; LEAL, MARIA CAROLINA B. DI MEDEIROS; CASTRO, ALEX; FERREIRA, ANTONIO GILBERTO; COMINETTI, MARCIA REGINA; ANIBAL, FERNANDA DE FREITAS. Phenylalanine and COVID-19: Tracking disease severity markers. International Immunopharmacology, v. 101, n. A, . (20/13939-7, 14/50867-3, 19/16135-9)
GONCALVES, JOSUE M.; LIMA, IRLAN S.; AZEREDO, NATHALIA F. B.; ROCHA, DIEGO P.; DE SIERVO, ABNER; ANGNES, LUCIO. iVCe-Layered Double Hydroxide as Multifunctional Nanomaterials for Energy and Sensor Application. FRONTIERS IN MATERIALS, v. 8, . (17/13137-5, 20/00325-0, 07/08244-5, 07/54829-5, 18/16896-7, 14/50867-3)
PINTO, LICARION; SALES FONTES JARDIM, ISABEL CRISTINA; RUTLEDGE, DOUGLAS NEIL; BREITKREITZ, MARCIA CRISTINA. Multiblock modelling on the study of the kinetic degradation of rosuvastatin calcium in the presence of retention time shifts and rank deficiency. Analytica Chimica Acta, v. 1133, p. 77-87, . (14/50867-3, 16/05636-9)
DA SILVEIRA, GESSICA DOMINGOS; BRESSAN, LUCAS PANES; SCHMIDT, MARCELLA EMILIA PETRA; DAL MOLIN, THAIS RAMOS; TEIXEIRA, CARLOS ALBERTO; POPPI, RONEI JESUS; DA SILVA, JOSE ALBERTO FRACASSI. Electrochemical behavior of 5-type phosphodiesterase inhibitory drugs in solid state by voltammetry of immobilized microparticles. Journal of Solid State Electrochemistry, v. 24, n. 8, SI, . (14/50867-3, 18/06478-3, 18/13496-8)
PELIN, JULIANE N. B. D.; GERBELLI, BARBARA B.; EDWARDS-GAYLE, CHARLOTTE J. C.; AGUILAR, ANDREA M.; CASTELLETTO, VALERIA; HAMLEY, IAN W.; ALVES, WENDEL A.. Amyloid Peptide Mixtures: Self-Assembly, Hydrogelation, Nematic Ordering, and Catalysts in Aldol Reactions. Langmuir, v. 36, n. 11, p. 2767-2774, . (14/50867-3, 17/02317-2, 18/05888-3, 18/12535-0, 15/20446-9)
MELLO, LUCAS R.; AGUIAR, RODRIGO B.; YAMADA, RENATA Y.; MORAES, JANE Z.; HAMLEY, IAN W.; ALVES, WENDEL A.; REZA, MEHEDI; RUOKOLAINEN, JANNE; SILVA, EMERSON R.. Amphipathic design dictates self-assembly, cytotoxicity and cell uptake of arginine-rich surfactant-like peptides. JOURNAL OF MATERIALS CHEMISTRY B, v. 8, n. 12, p. 2495-2507, . (15/24018-1, 14/50867-3, 17/02317-2, 16/24409-3)
SOUZA, JULIANA S.; ALVES, WENDEL A.. Influence of Preparation Methodology on the Photocatalytic Activity of Nitrogen Doped Titanate and TiO2 Nanotubes. Journal of Nanoscience and Nanotechnology, v. 20, n. 9, p. 5390-5401, . (17/11395-7, 14/50867-3, 15/24018-1)
NUNEZ, FREDDY A.; CASTRO, ANA C. H.; DE OLIVEIRA, VIVIAN L.; LIMA, ARIANE C.; OLIVEIRA, JAMILLE R.; DE MEDEIROS, GIULIANA X.; SASAHARA, GREYCE L.; SANTOS, KEITY S.; LANFREDI, ALEXANDRE J. C.; ALVES, WENDEL A.. Electrochemical Immunosensors Based on Zinc Oxide Nanorods for Detection of Antibodies Against SARS-CoV-2 Spike Protein in Convalescent and Vaccinated Individuals. ACS BIOMATERIALS SCIENCE & ENGINEERING, v. 9, n. 1, p. 16-pg., . (17/02317-2, 14/50867-3)
ARENAS BUELVAS, DAINA DAYANA; CAMARGO, LUAN PEREIRA; IAGLA SALGADO, INGRID KAUANA; SANTANA VICENTIN, BRUNO LUIZ; VALEZI, DANIEL FARINHA; DALL'ANTONIA, LUIZ HENRIQUE; TEIXEIRA TARLEY, CESAR RICARDO; DI MAURO, EDUARDO. Study and optimization of the adsorption process of methylene blue dye in reusable polyaniline-magnetite composites. Synthetic Metals, v. 292, p. 13-pg., . (14/50867-3)
DE ASSIS, SAMUEL CHAGAS; MORGADO, DANIELLA LURY; SCHEIDT, DESIREE TAMARA; DE SOUZA, SAMARA SILVA; CAVALLARI, MARCO ROBERTO; ANDO JR, OSWALDO HIDEO; CARRILHO, EMANUEL. Review of Bacterial Nanocellulose-Based Electrochemical Biosensors: Functionalization, Challenges, and Future Perspectives. BIOSENSORS-BASEL, v. 13, n. 1, p. 30-pg., . (14/50867-3)
GERBELLI, BARBARA B.; FILHO, PEDRO L. O.; CORTEZ, BRUNA; SODRE, PEDRO T.; COUTINHO-NETO, MAURICIO D.; HAMLEY, IAN W.; SEITSONEN, JANI; ALVES, WENDEL A.. Interaction between glyphosate pesticide and amphiphilic peptides for colorimetric analysis. NANOSCALE ADVANCES, v. 4, n. 17, p. 8-pg., . (14/50867-3, 17/02317-2, 20/13204-7, 18/05888-3, 19/12301-1, 20/02192-8)

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Filed patent(s) as a result of this research project

BLUCHEM BR512021003058-3 - Centro Nacional de Pesquisa em Energia e Materiais (CNPEM) ; Universidade Estadual de Campinas (UNICAMP) . Lauro Tatsuo Kubota ; Renato Sousa Lima ; José Guilherme Ribas Sophia Franco ; Lourenço Henrique Bittar Vidotto ; Guilherme Francisco de Freitas - December 2021, 09